Start page

Our main focus

The Max Planck Research Group investigates the interaction of the immune system with the organism, in particular the interaction of different cells of the immune system in local networks and with cells of other organ systems.

Learn more

WüSI welcomes Dominic Grün

We are very excited to announce that Dominic Grün has joined the Institute of Systems Immunology! Prof. Grün, is moving from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg, where he heads the research group “Quantitative Single Cell Biology”. He is joining WüSI as the director of a new chair that was founded with support of the Bavarian Network for Artificial Intelligence with the aim of advancing Biomedical Research at the intersection of Artificial Intelligence and Systems Immunology. Prof. Grün will have a double-affiliation with the Center for Artificial Intelligence in Data Science in Würzburg (CAIDAS) and WüSI and will continue to pioneer novel experimental and computational approaches in Single Cell Biology, Spatial Transcriptomics and Systems Immunology.
His research interests span from development, hematopoiesis and immunology to the functional microarchitecture of tissue niches in health and disease. Supported by an ERC Consolidator Grant he investigates the hematopoietic bone marrow niche by combining single-cell sequencing and genome-wide single-molecule FISH imaging, facilitated by the development of novel artificial intelligence and computational machine learning methods. He is already closely collaboratiog with WüSI scientists within the german priority program for Innate Lymphoid Cells (link: https://doi.org/10.1016/j.immuni.2020.09.002)
Check out his homepage for more information.

New Publications

Effector differentiation downstream of lineage commitment in ILC1 is driven by Hobit across tissues, Nature Immunology, 2021 open access

Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration, Nature Cell Biology, 2021

Neutrophils self-limit swarming to contain bacterial growth in vivo, Science, 2021

BATF3 programs CD8+ T cell memory, Nature Immunology, 2020

In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors, Immunity, 2020

A human liver cell atlas reveals heterogeneity and epithelial progenitors, Nature, 2019

News

Hobit Turns Immune Cells Into Killers ILCs are rapid reaction forces that reside in tissues to combat infections and tumors. WüSI scientist now show how these cells turn into effector cells…Learn more

Start-stop System of Hunting Immune Cells How immune cells coordinate their swarming behaviour to effectively eliminate pathogens: A publication in "Science" presents new findings...Learn more

New therapeutic approach against COVID-19 In January 2021, a supraregional research project will start that aims to develop a targeted therapy against SARS-CoV-2. Scientists from the University of Würzburg are involved....Learn more (german)

Immune cells as guests in the tissue Specialized immune cells settle permanently in tissues of the body and build “local task forces”. Wuerzburger scientists... Learn more

Memory training for the immune system The immune system will memorize the pathogen after an infection and can therefore react promptly after reinfection with the same pathogen. Now, scientists at the University of Würzburg...Learn more

WüSI's publication is among the top 10 most read Immunity articles.

New review articles is out from Katarzyna Jobin.

Research

Chairs

Junior Groups

Graduate Programs

Logo der GSLS

Graduate School for Life Science

The Graduate School of Life Sciences (GSLS) provides structured doctoral research training in a highly interdisciplinary research environment.

[Translate to Englisch:] Logo der imprs-iem

IMPRS-IEM in Freiburg

The International Max Planck Research School for Immunobiology, Epigenetics and Metabolism (IMPRS-IEM) - a joint international PhD Programme of the Max Planck Institute of Immunobiology and Epigenetics and the University of Freiburg