Würzburg Institute of Systems Immunology

The Max Planck Research Group

The Max Planck Research Group for Systems Immunology is a collaborative effort between the Julius Maximilian University of Würzburg (JMU) and the Max Planck Society (MPG) aimed at promoting excellent immunological research. Around 50 researchers from more than 20 countries are working together to understand the basis of a successful immune response against infectious agents, chronic inflammatory diseases, and tumors. Their ultimate goal is to develop new concepts and strategies for vaccines and immunotherapies.

To achieve this, the group is investigating the development and function of the immune system holistically at multiple levels. They are conducting high-resolution analyses of single molecules and cells, examining complex cellular networks within organs, and exploring systemic interactions in the body and with the environment. These research goals align well with the internationally visible research on infectious diseases and immunotherapies at the Würzburg Life Science Campus.

Max Planck Research Group

Job offers

Press Review

"Immune cells in single file: How a messenger molecule keeps dendritic cells together on their patrol through the tissue" - Medical press - July 17, 2023

“Greater gender equality in science will lead to a stronger scientific community” Max-Planck-Gesellschaft, 75th anniversary (Female scientists and historical trailblazers) - 04/2023

On the trail of immune cells

Carlos Talavera-López has recently been appointed junior professor of systems immunology at the University of Würzburg. His special focus is on processes inside cells. To do so, he relies on deep learning methods.

More information of Carlos Talavera-López

Bild von Prof. Dr. Carlos Talavera-López Systemimmunologie Immunologie Würzburg — Picture: Anika Grafen / Max-Planck-research group for systems immunology

Institute of Systems Immunology

Versbacher Str. 9, 97078 Würzburg

Phone.: +49 931 31-89740
Email

Team

Selected Publications

Resident regulatory T cells reflect the immune history of individual lymph nodes, Science Immunology 2023

Mitochondrial dysfunction promotes the transition of precursor to terminally exhausted T cells through HIF-1α-mediated glycolytic reprogramming, Nat Commun 2023

Resident regulatory T cells reflect the immune history of individual lymph nodes, Science Immunology 2023

Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks., Immunity. 2023

VarID2 quantifies gene expression noise dynamics and unveils functional heterogeneity of ageing hematopoietic stem cells, Genome Biol., 2023

CD4⁺ T cell-induced inflammatory cell death controls immune-evasive tumours, nature, 2023

ILC3s restrict the dissemination of intestinal bacteria to safeguard liver regeneration after surgery, Cell Press, 2023

Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes, Immunity, 2022

Developmental dynamics of two bipotent thymic epithelial progenitor type, Nature, 2022

Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches, Immunity, 222

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Immunology in Würzburg

Immunologie in Würzburg Systemimmunologie

News

Anna Lippert WueSi_systems immunology_Vogel

Funding for Würzburg Biophysicist

Junior Professor Anna Lippert from the Institute of Systems Immunology at the University of Würzburg is receiving EUR 10,000 from the Vogel Foundation Dr Eckernkamp to support her research.

WueSi_HighlyCited_Grün_Systemimmunologie

Highly Cited Researchers 2023

Their work is most frequently cited in publications of other scientists. Researchers from the University of Würzburg are therefore included in the Highly Cited Researchers 2023 list.

Institute for systems immunology Vaeth Väth_T-Cells Exhaustion

Preventing the Exhaustion of T Cells

In the immune system's fight against cancer and infections, the T cells often lose their power. The team of Würzburg immunologist Martin Vaeth has found a possible explanation for this phenomenon.

Immune guardians in the lymph node

Contrary to prior belief, certain T-cells remain in lymph nodes for a long time and store information about immune reactions there. That’s been discovered by researchers at the University of Würzburg and the RWTH Aachen

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Research

Chairs

Photo Microskop Immunology Systems immunology Reseach Würzburg

Junior Groups

Graduate Programs

Graduate School of Life Sciences

The Graduate School of Life Sciences (GSLS) provides structured doctoral research training in a highly interdisciplinary research environment.

IMPRS-IEM in Freiburg

The International Max Planck Research School for Immunobiology, Epigenetics and Metabolism (IMPRS-IEM) - a joint international PhD Programme of the Max Planck Institute of Immunobiology and Epigenetics and the University of Freiburg

Medizin, Geb. E6

Systems Immunology Würzburg