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    Core Unit Systemmedizin

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    2022[ to top ]
    • Helicobacter pylori shows tropism to gastric differentiated pit cells dependent on urea chemotaxis. Aguilar, Carmen; Pauzuolis, Mindaugas; Pompaiah, Malvika; Vafadarnejad, Ehsan; Arampatzi, Panagiota; Fischer, Mara; Narres, Dominik; Neyazi, Mastura; Kayisoglu, Özge; Sell, Thomas; Blüthgen, Nils; Morkel, Markus; Wiegering, Armin; Germer, Christoph-Thomas; Kircher, Stefan; Rosenwald, Andreas; Saliba, Antoine-Emmanuel; Bartfeld, Sina in Nature Communications (2022). 13(1) 5878.
    • Eine Einzelzell-{RNA}-Sequenzierung identifiziert Metabolismus und {CD}52 als neue Angriffspunkte in Ibrutinib-persistenten Mantelzelllymphomzellen. Fuhr, Viktoria; Vafadarnejad, Ehsan; Dietrich, Oliver; Arampatzi, Panagiota; Riedel, Angela; Saliba, Antoine-Emmanuel; Rosenwald, Andreas; Rauert-Wunderlich, Hilka in Die Pathologie (2022).
    • Temperature and livestock grazing trigger transcriptome responses in bumblebees along an elevational gradient. Brenzinger, Kristof; Maihoff, Fabienne; Peters, Marcell K.; Schimmer, Leonie; Bischler, Thorsten; Classen, Alice in iScience (2022). 25(10)
    • Dynamics of monocyte-derived macrophage diversity in experimental myocardial infarction. Rizzo, Giuseppe; Gropper, Julius; Piollet, Marie; Vafadarnejad, Ehsan; Rizakou, Anna; Bandi, Sourish Reddy; Arampatzi, Panagiota; Krammer, Tobias; DiFabion, Nina; Dietrich, Oliver; Arias-Loza, Anahi Paula; Prinz, Marco; Mack, Matthias; Schlepckow, Kai; Haass, Christian; Silvestre, Jean S{\’{e}}bastien; Zernecke, Alma; Saliba, Antoine Emmanuel; Cochain, Cl{\’{e}}ment in Cardiovascular Research (2022).
    • hnRNP R negatively regulates transcription by modulating the association of P-TEFb with 7SK and BRD4. Ji, Changhe; Deng, Chunchu; Antor, Katharina; Bischler, Thorsten; Schneider, Cornelius; Fischer, Utz; Sendtner, Michael; Briese, Michael in EMBO reports (2022). e55432.
    • Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T~cells in distinct cellular niches. Dähling, Sabrina; Mansilla, Ana Maria; Knöpper, Konrad; Grafen, Anika; Utzschneider, Daniel T.; Ugur, Milas; Whitney, Paul G.; Bachem, Annabell; Arampatzi, Panagiota; Imdahl, Fabian; Kaisho, Tsuneyasu; Zehn, Dietmar; Klauschen, Frederick; Garbi, Natalio; Kallies, Axel; Saliba, Antoine-Emmanuel; Gasteiger, Georg; Bedoui, Sammy; Kastenmüller, Wolfgang in Immunity (2022). 55(4) 656–670.e8.
    • Spacer prioritization in CRISPR–Cas9 immunity is enabled by the leader RNA. Liao, Chunyu; Sharma, Sahil; Svensson, Sarah L.; Kibe, Anuja; Weinberg, Zasha; Alkhnbashi, Omer S.; Bischler, Thorsten; Backofen, Rolf; Caliskan, Neva; Sharma, Cynthia M.; Beisel, Chase L. in Nature Microbiology (2022).
    • Liraglutide + PYY3-36 Combination Therapy Mimics Effects of Roux-en-Y Bypass on Early NAFLD Whilst Lacking-Behind in Metabolic Improvements. Metzner, Valentin; Herzog, Gloria; Heckel, Tobias; Bischler, Thorsten; Hasinger, Julia; Otto, Christoph; Fassnacht, Martin; Geier, Andreas; Seyfried, Florian; Dischinger, Ulrich in Journal of Clinical Medicine (2022). 11(3) 753.
    • Neurodegeneration by α-synuclein-specific T cells in AAV-A53T-α-synuclein Parkinson’s disease mice. Karikari, Akua A.; McFleder, Rhonda L.; Ribechini, Eliana; Blum, Robert; Bruttel, Valentin; Knorr, Susanne; Gehmeyr, Mona; Volkmann, Jens; Brotchie, Jonathan M.; Ahsan, Fadhil; Haack, Beatrice; Monoranu, Camelia-Maria; Keber, Ursula; Yeghiazaryan, Rima; Pagenstecher, Axel; Heckel, Tobias; Bischler, Thorsten; Wischhusen, Jörg; Koprich, James B.; Lutz, Manfred B.; Ip, Chi Wang in Brain, Behavior, and Immunity (2022).
    • Homeostatic calcium fluxes, {ER} calcium release, {SOCE}, and calcium oscillations in cultured astrocytes are interlinked by a small calcium toolkit. Schulte, Annemarie; Bieniussa, Linda; Gupta, Rohini; Samtleben, Samira; Bischler, Thorsten; Doering, Kristina; Sodmann, Philipp; Rittner, Heike; Blum, Robert in Cell Calcium (2022). 101 102515.
    2021[ to top ]
    • Roux-en-Y Gastric Bypass and Caloric Restriction but Not Gut Hormone-Based Treatments Profoundly Impact the Hypothalamic Transcriptome in Obese Rats. Dischinger, Ulrich; Heckel, Tobias; Bischler, Thorsten; Hasinger, Julia; Königsrainer, Malina; Schmitt-Böhrer, Angelika; Otto, Christoph; Fassnacht, Martin; Seyfried, Florian; Hankir, Mohammed Khair in Nutrients (2021). 14(1) 116.
    • Fibromyalgia vs small fiber neuropathy: diverse keratinocyte transcriptome signature. Karl, Franziska; Bischler, Thorsten; Egenolf, Nadine; Evdokimov, Dimitar; Heckel, Tobias; Üçeyler, Nurcan in PAIN (2021). 162 2569–2577.
    • {The Rsm (Csr) post-transcriptional regulatory pathway coordinately controls multiple CRISPR–Cas immune systems}. Campa, Aroa Rey; Smith, Leah M; Hampton, Hannah G; Sharma, Sahil; Jackson, Simon A; Bischler, Thorsten; Sharma, Cynthia M; Fineran, Peter C in Nucleic Acids Research (2021).
    • Effector differentiation downstream of lineage commitment in {ILC}1s is driven by Hobit across tissues. Friedrich, Christin; Taggenbrock, Renske L. R. E.; Doucet-Ladev{\`{e}}ze, R{\’{e}}mi; Golda, Gosia; Moenius, Rebekka; Arampatzi, Panagiota; Kragten, Natasja A. M.; Kreymborg, Katharina; de Agüero, Mercedes Gomez; Kastenmüller, Wolfgang; Saliba, Antoine-Emmanuel; Grün, Dominic; van Gisbergen, Klaas P. J. M.; Gasteiger, Georg in Nature Immunology (2021). 22(10) 1256–1267.
    • The healing myocardium mobilizes a distinct B-cell subset through a {CXCL}13-{CXCR}5-dependent mechanism. Heinrichs, Margarete; Ashour, DiyaaElDin; Siegel, Johanna; Büchner, Lotte; Wedekind, Georg; Heinze, Katrin G; Arampatzi, Panagiota; Saliba, Antoine-Emmanuel; Cochain, Clement; Hofmann, Ulrich; Frantz, Stefan; Ramos, Gustavo Campos in Cardiovascular Research (2021).
    • Accumulation of cytotoxic T cells in the aged {CNS} leads to axon degeneration and contributes to cognitive and motor decline. Groh, Janos; Knöpper, Konrad; Arampatzi, Panagiota; Yuan, Xidi; Lö{\ss}lein, Lena; Saliba, Antoine-Emmanuel; Kastenmüller, Wolfgang; Martini, Rudolf in Nature Aging (2021). 1(4) 357–367.
    • Noncanonical crRNAs derived from host transcripts enable multiplexable RNA detection by Cas9. Jiao, Chunlei; Sharma, Sahil; Dugar, Gaurav; Peeck, Natalia L.; Bischler, Thorsten; Wimmer, Franziska; Yu, Yanying; Barquist, Lars; Schoen, Christoph; Kurzai, Oliver; Sharma, Cynthia M.; Beisel, Chase L. in Science (2021).
    • Homozygous {BCMA} gene deletion in response to anti-{BCMA} {CAR} T cells in a patient with multiple myeloma. Vi{\`{a}}, Matteo C. Da; Dietrich, Oliver; Truger, Marietta; Arampatzi, Panagiota; Duell, Johannes; Heidemeier, Anke; Zhou, Xiang; Danhof, Sophia; Kraus, Sabrina; Chatterjee, Manik; Meggendorfer, Manja; Twardziok, Sven; Goebeler, Maria-Elisabeth; Topp, Max S.; Hudecek, Michael; Prommersberger, Sabrina; Hege, Kristen; Kaiser, Shari; Fuhr, Viktoria; Weinhold, Niels; Rosenwald, Andreas; Erhard, Florian; Haferlach, Claudia; Einsele, Hermann; Kortüm, K. Martin; Saliba, Antoine-Emmanuel; Rasche, Leo in Nature Medicine (2021).
    • Time-Resolved {scRNA}-Seq Tracks the Adaptation of a Sensitive {MCL} Cell Line to Ibrutinib Treatment. Fuhr, Viktoria; Vafadarnejad, Ehsan; Dietrich, Oliver; Arampatzi, Panagiota; Riedel, Angela; Saliba, Antoine-Emmanuel; Rosenwald, Andreas; Rauert-Wunderlich, Hilka in International Journal of Molecular Sciences (2021). 22(5) 2276.
    • {MAPS} integrates regulation of actin-targeting effector {SteC} into the virulence control network of Salmonella small {RNA} {PinT}. Santos, Sara Correia; Bischler, Thorsten; Westermann, Alexander J.; Vogel, Jörg in Cell Reports (2021). 34(5) 108722.
    • Terminally Differentiated CD4+ T Cells Promote Myocardial Inflammaging. Delgobo, Murilo; Heinrichs, Margarete; Hapke, Nils; Ashour, DiyaaElDin; Appel, Marc; Srivastava, Mugdha; Heckel, Tobias; Spyridopoulos, Ioakim; Hofmann, Ulrich; Frantz, Stefan; Ramos, Gustavo Campos in Frontiers in Immunology (2021). 12
    • Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia. Chumduri, Cindrilla; Gurumurthy, Rajendra Kumar; Berger, Hilmar; Dietrich, Oliver; Kumar, Naveen; Koster, Stefanie; Brinkmann, Volker; Hoffmann, Kirstin; Drabkina, Marina; Arampatzi, Panagiota; Son, Dajung; Klemm, Uwe; Mollenkopf, Hans-Joachim; Herbst, Hermann; Mangler, Mandy; Vogel, Jörg; Saliba, Antoine-Emmanuel; Meyer, Thomas F. in Nature Cell Biology (2021). 23(2) 184–197.
    2020[ to top ]
    • Tetrachloroethene respiration in Sulfurospirillum species is regulated by a two-component system as unraveled by comparative genomics, transcriptomics, and regulator binding studies. Esken, Jens; Goris, Tobias; Gadkari, Jennifer; Bischler, Thorsten; Förstner, Konrad U.; Sharma, Cynthia M.; Diekert, Gabriele; Schubert, Torsten in {MicrobiologyOpen} (2020).
    • A Repeat-Associated Small {RNA} Controls the Major Virulence Factors of Helicobacter pylori. Eisenbart, Sara K.; Alzheimer, Mona; Pernitzsch, Sandy R.; Dietrich, Sascha; Stahl, Stephanie; Sharma, Cynthia M. in Molecular Cell (2020).
    • Dynamics of Cardiac Neutrophil Diversity in Murine Myocardial Infarction. Vafadarnejad, Ehsan; Rizzo, Giuseppe; Krampert, Laura; Arampatzi, Panagiota; Arias-Loza, Paula Anahi; Nazzal, Yara; Rizakou, Anna; Knochenhauer, Tim; Bandi, Sourish Reddy; Nugroho, Vallery Audy; Schulz, Dirk JJ; Roesch, Melanie; Alayrac, Paul; Vilar, Jos{\’{e}}; Silvestre, Jean-S{\’{e}}bastien; Zernecke, Alma; Saliba, Antoine-Emmanuel; Cochain, Clement in Circulation Research (2020).
    • The minimal meningococcal ProQ protein has an intrinsic capacity for structure-based global RNA recognition. Bauriedl, Saskia; Gerovac, Milan; Heidrich, Nadja; Bischler, Thorsten; Barquist, Lars; Vogel, Jörg; Schoen, Christoph in Nature Communications (2020). 11(1) 2823-.
    • {IL}-12 from endogenous {cDC}1, and not vaccine {DC}, is required for Th1 induction. Ashour, DiyaaElDin; Arampatzi, Panagiota; Pavlovic, Vladimir; Förstner, Konrad U.; Kaisho, Tsuneyasu; Beilhack, Andreas; Erhard, Florian; Lutz, Manfred B. in {JCI} Insight (2020). 5(10)
    • Improved bacterial {RNA}-seq by Cas9-based depletion of ribosomal {RNA} reads. Prezza, Gianluca; Heckel, Tobias; Dietrich, Sascha; Homberger, Christina; Westermann, Alexander J; Vogel, Jörg in {RNA} (2020). rna.075945.120.
    • Single-cell transcriptomic profiling maps monocyte/macrophage transitions after myocardial infarction in mice. Rizzo, Giuseppe; Vafadarnejad, Ehsan; Arampatzi, Panagiota; Silvestre, Jean-Sebastien; Zernecke, Alma; Saliba, Antoine-Emmanuel; Cochain, Clement in bioRxiv (2020).
    • Integrative functional genomics decodes herpes simplex virus 1. Whisnant, Adam W.; Jürges, Christopher S.; Hennig, Thomas; Wyler, Emanuel; Prusty, Bhupesh; Rutkowski, Andrzej J.; L’hernault, Anne; Djakovic, Lara; Göbel, Margarete; Döring, Kristina; Menegatti, Jennifer; Antrobus, Robin; Matheson, Nicholas J.; Künzig, Florian W. H.; Mastrobuoni, Guido; Bielow, Chris; Kempa, Stefan; Liang, Chunguang; Dandekar, Thomas; Zimmer, Ralf; Landthaler, Markus; Grässer, Friedrich; Lehner, Paul J.; Friedel, Caroline C.; Erhard, Florian; Dölken, Lars in Nature Communications (2020). 11(1) 2038-.
    • The Influence of Met Receptor Level on {HGF}-Induced Glycolytic Reprogramming in Head and Neck Squamous Cell Carcinoma. Boschert, Verena; Klenk, Nicola; Abt, Alexander; Raman, Sudha Janaki; Fischer, Markus; Brands, Roman C.; Seher, Axel; Linz, Christian; Müller-Richter, Urs D. A.; Bischler, Thorsten; Hartmann, Stefan in International Journal of Molecular Sciences (2020). 21(2) 471.
    2019[ to top ]
    • Conditional Hfq Association with Small Noncoding RNAs in Pseudomonas aeruginosa Revealed through Comparative UV Cross-Linking Immunoprecipitation Followed by High-Throughput Sequencing. Chihara, K; Bischler, T; Barquist, L; Monzon, V A; Noda, N; Vogel, J; Tsuneda, S in mSystems (2019). 4(6)
    • Efficient depletion of ribosomal RNA for RNA sequencing in planarians. Kim, Iana V.; Ross, Eric J.; Dietrich, Sascha; Döring, Kristina; Sánchez Alvarado, Alejandro; Kuhn, Claus-D. in BMC Genomics (2019). 20(1) 909.
    • Sensory profiles and immune-related expression patterns of patients with and without neuropathic pain after peripheral nerve lesion. Held, Melissa; Karl, Franziska; Vlckova, Eva; Rajdova, Aneta; Escolano-Lozano, Fabiola; Stetter, Christian; Bharti, Richa; Förstner, Konrad U.; Leinders, Mathias; Du{\v{s}}ek, Ladislav; Birklein, Frank; Bednarik, Josef; Sommer, Claudia; Ü{\c{c}}eyler, Nurcan in {PAIN} (2019). 160(10) 2316–2327.
    • {RAL} {GTPases} mediate multiple myeloma cell survival and are activated independently of oncogenic {RAS}. Seibold, Marcel; Stühmer, Thorsten; Kremer, Nadine; Mottok, Anja; Scholz, Claus-Jürgen; Schlosser, Andreas; Leich, Ellen; Holzgrabe, Ulrike; Brünnert, Daniela; Barrio, Santiago; Kortüm, K. Martin; Solimando, Antonio G.; Chatterjee, Manik; Einsele, Hermann; Rosenwald, Andreas; Bargou, Ralf C.; Steinbrunn, Torsten in Haematologica (2019). haematol.2019.223024.
    • Hierarchy of mono- and biallelic {TP}53 alterations in multiple myeloma cell fitness. Munawar, Umair; Rasche, Leo; Müller, Nicole; Vogt, Cornelia; Da-Via, Matteo; Haertle, Larissa; Arampatzi, Panagiota; Dietrich, Sascha; Roth, Markus; Garitano-Trojaola, Andoni; Steinhardt, Maximilian Johannes; Strifler, Susanne; Gallardo, Miguel; Martinez-Lopez, Joaquin; Bargou, Ralf C.; Heckel, Tobias; Einsele, Hermann; Stühmer, Thorsten; Kortüm, K. Martin; Barrio, Santiago in Blood (2019). 134(10) 836–840.
    • Time-resolved single-cell transcriptomics uncovers dynamics of cardiac neutrophil diversity in murine myocardial infarction. Vafadarnejad, Ehsan; Rizzo, Giuseppe; Krampert, Laura; Arampatzi, Panagiota; Nugroho, Vallery Audy; Schulz, Dirk; Roesch, Melanie; Alayrac, Paul; Vilar, Jose; Silvestre, Jean-S{\’e}bastien; Zernecke, Alma; Saliba, Antoine-Emmanuel; Cochain, Cl{\’e}ment in bioRxiv (2019).
    • {scSLAM}-seq reveals core features of transcription dynamics in single cells. Erhard, Florian; Baptista, Marisa A. P.; Krammer, Tobias; Hennig, Thomas; Lange, Marius; Arampatzi, Panagiota; Jürges, Christopher S.; Theis, Fabian J.; Saliba, Antoine-Emmanuel; Dölken, Lars in Nature (2019). 571(7765) 419–423.
    • Identification of Cholecystokinin by Genome-Wide Profiling as Potential Mediator of Serotonin-Dependent Behavioral Effects of Maternal Separation in the Amygdala. Weidner, Magdalena T.; Lardenoije, Roy; Eijssen, Lars; Mogavero, Floriana; Groodt, Lilian P. M. T. De; Popp, Sandy; Palme, Rupert; Förstner, Konrad U.; Strekalova, Tatyana; Steinbusch, Harry W. M.; Schmitt-Böhrer, Angelika G.; Glennon, Jeffrey C.; Waider, Jonas; van den Hove, Daniel L. A.; Lesch, Klaus-Peter in Frontiers in Neuroscience (2019). 13
    • Contribution of {LTi} and {TH}17 cells to {B} cell aggregate formation in the central nervous system in a mouse model of multiple sclerosis. Schropp, Verena; Rohde, Jörn; Rovituso, Damiano M.; Jabari, Samir; Bharti, Richa; Kuerten, Stefanie in Journal of Neuroinflammation (2019). 16(1) 111.
    • Integrative functional genomics decodes herpes simplex virus 1. Whisnant, Adam W.; J{\"u}rges, Christopher S.; Hennig, Thomas; Wyler, Emanuel; Prusty, Bhupesh; Rutkowski, Andrzej J; L{\textquoteright}hernault, Anne; G{\"o}bel, Margarete; D{\"o}ring, Kristina; Menegatti, Jennifer; Antrobus, Robin; Matheson, Nicholas J.; K{\"u}nzig, Florian W.H.; Mastrobuoni, Guido; Bielow, Chris; Kempa, Stefan; Chunguang, Liang; Dandekar, Thomas; Zimmer, Ralf; Landthaler, Markus; Gr{\"a}sser, Friedrich; Lehner, Paul J.; Friedel, Caroline C.; Erhard, Florian; D{\"o}lken, Lars in bioRxiv (2019).
    • Characterization of the transcriptome of Haloferax volcanii, grown under four different conditions, with mixed RNA-Seq. Laass, Sebastian; Monzon, Vivian A.; Kliemt, Jana; Hammelmann, Matthias; Pfeiffer, Friedhelm; Förstner, Konrad U.; Soppa, Jörg in PLOS ONE (2019). 14(4) 1–24.
    • Cognate {Nonlytic} {Interactions} between {CD}8+ {T} {Cells} and {Breast} {Cancer} {Cells} {Induce} {Cancer} {Stem} {Cell}–like {Properties}. Stein, Roland G.; Ebert, Stefan; Schlahsa, Laura; Scholz, Claus J.; Braun, Matthias; Hauck, Petra; Horn, Evi; Monoranu, Camelia-Maria; Thiemann, Vincent J.; Wustrow, Michael P.; Häusler, Sebastian F.; Barrio, Itsaso Montalbán del; Stüber, Tanja N.; Wölfl, Matthias; Dietl, Johannes; Rosenwald, Andreas; Diessner, Joachim E.; Wöckel, Achim; Wischhusen, Jörg in Cancer Research (2019). 79(7) 1507–1519.
    • The small non-coding {RNA} {RsaE} influences extracellular matrix composition in {Staphylococcus} epidermidis biofilm communities. Schoenfelder, Sonja M. K.; Lange, Claudia; Prakash, Srinivasa Abishek; Marincola, Gabriella; Lerch, Maike F.; Wencker, Freya D. R.; Förstner, Konrad U.; Sharma, Cynthia M.; Ziebuhr, Wilma in PLOS Pathogens (2019). 15(3) e1007618.
    • {MicroRNA} expression correlates with disease recurrence and overall survival in oral squamous cell carcinoma. Moratin, Julius; Hartmann, Stefan; Brands, Roman C.; Horn, Dominik; Fuchs, Andreas; Mutzbauer, Grit; Seher, Axel; Scholz, Claus; Müller-Richter, Urs D.A.; Linz, Christian in Journal of Cranio-Maxillofacial Surgery (2019). 47(3) 523–529.
    • The identification of patient-specific mutations reveals dual pathway activation in most patients with melanoma and activated receptor tyrosine kinases in {BRAF}/{NRAS} wild-type melanomas. Appenzeller, Silke; Gesierich, Anja; Thiem, Alexander; Hufnagel, Anita; Jessen, Christina; Kneitz, Hermann; Regensburger, Martina; Schmidt, Cornelia; Zirkenbach, Vanessa; Bischler, Thorsten; Schilling, Bastian; Siedel, Claudia; Goebeler, Maria-Elisabeth; Houben, Roland; Schrama, David; Gehrig, Andrea; Rost, Simone; Maurus, Katja; Bargou, Ralf; Rosenwald, Andreas; Schartl, Manfred; Goebeler, Matthias; Meierjohann, Svenja in Cancer (2019). 125(4) 586–600.
    • The {Major} {RNA}-{Binding} {Protein} {ProQ} {Impacts} {Virulence} {Gene} {Expression} in {Salmonella} enterica {Serovar} {Typhimurium}. Westermann, Alexander J.; Venturini, Elisa; Sellin, Mikael E.; Förstner, Konrad U.; Hardt, Wolf-Dietrich; Vogel, Jörg in mBio (2019). 10(1) e02504–18.
    2018[ to top ]
    • Clinical implications of fracture-associated vascular damage in extremity and pelvic trauma. Gilbert, F.; Schneemann, C.; Scholz, C. J.; Kickuth, R.; Meffert, R. H.; Wildenauer, R.; Lorenz, U.; Kellersmann, R.; Busch, A. in BMC Musculoskeletal Disorders (2018). 19(1) 404.
    • Post-transcriptional gene regulation by an {Hfq}-independent small {RNA} in {Caulobacter} crescentus. Fröhlich, Kathrin S.; Förstner, Konrad U.; Gitai, Zemer in Nucleic Acids Research (2018). 46(20) 10969–10982.
    • Genome organization and {DNA} accessibility control antigenic variation in trypanosomes. Müller, Laura S. M.; Cosentino, Ra{\’{u}}l O.; Förstner, Konrad U.; Guizetti, Julien; Wedel, Carolin; Kaplan, Noam; Janzen, Christian J.; Arampatzi, Panagiota; Vogel, Jörg; Steinbiss, Sascha; Otto, Thomas D.; Saliba, Antoine-Emmanuel; Sebra, Robert P.; Siegel, T. Nicolai in Nature (2018). 563(7729) 121–125.
    • Neonatally imprinted stromal cell subsets induce tolerogenic dendritic cells in mesenteric lymph nodes. Pezoldt, Joern; Pasztoi, Maria; Zou, Mangge; Wiechers, Carolin; Beckstette, Michael; Thierry, Guilhem R.; Vafadarnejad, Ehsan; Floess, Stefan; Arampatzi, Panagiota; Buettner, Manuela; Schweer, Janina; Fleissner, Diana; Vital, Marius; Pieper, Dietmar H.; Basic, Marijana; Dersch, Petra; Strowig, Till; Hornef, Mathias; Bleich, Andr{\’{e}}; Bode, Ulrike; Pabst, Oliver; Baj{\’{e}}noff, Marc; Saliba, Antoine-Emmanuel; Huehn, Jochen in Nature Communications (2018). 9(1)
    • {RNase} {E} cleavage shapes the transcriptome of {Rhodobacter} sphaeroides and strongly impacts phototrophic growth. Förstner, Konrad U.; Reuscher, Carina M.; Haberzettl, Kerstin; Weber, Lennart; Klug, Gabriele in Life Science Alliance (2018). 1(4) e201800080.
    • Panel {Sequencing} {Shows} {Recurrent} {Genetic} {FAS} {Alterations} in {Primary} {Cutaneous} {Marginal} {Zone} {Lymphoma}. Maurus, Katja; Appenzeller, Silke; Roth, Sabine; Kuper, Jochen; Rost, Simone; Meierjohann, Svenja; Arampatzi, Panagiota; Goebeler, Matthias; Rosenwald, Andreas; Geissinger, Eva; Wobser, Marion in Journal of Investigative Dermatology (2018). 138(7) 1573–1581.
    • A New Bioactive Compound From the Marine Sponge-Derived Streptomyces sp. {SBT}348 Inhibits Staphylococcal Growth and Biofilm Formation. Balasubramanian, Srikkanth; Skaf, Joseph; Holzgrabe, Ulrike; Bharti, Richa; Förstner, Konrad U.; Ziebuhr, Wilma; Humeida, Ute H.; Abdelmohsen, Usama R.; Oelschlaeger, Tobias A. in Frontiers in Microbiology (2018). 9
    • Global {Maps} of {ProQ} {Binding} {In} {Vivo} {Reveal} {Target} {Recognition} via {RNA} {Structure} and {Stability} {Control} at {mRNA} 3′ {Ends}. Holmqvist, Erik; Li, Lei; Bischler, Thorsten; Barquist, Lars; Vogel, Jörg in Molecular Cell (2018). 70(5) 971–982.e6.
    • The {Probiotic} {Escherichia} coli {Strain} {Nissle} 1917 {Combats} {Lambdoid} {Bacteriophages} stx and λ. Bury, Susanne; Soundararajan, Manonmani; Bharti, Richa; von Bünau, Rudolf; Förstner, Konrad U.; Oelschlaeger, Tobias A. in Frontiers in Microbiology (2018). 9
    • Computational {Analysis} of {RNA}–{Protein} {Interactions} via {Deep} {Sequencing}. Li, Lei; Förstner, Konrad U.; Chao, Yanjie in Transcriptome {Data} {Analysis} (2018). 171–182.
    • Single-{Cell} {RNA}-{Seq} {Reveals} the {Transcriptional} {Landscape} and {Heterogeneity} of {Aortic} {Macrophages} in {Murine} {Atherosclerosis}. Cochain, Clément; Vafadarnejad, Ehsan; Arampatzi, Panagiota; Jaroslav, Pelisek; Winkels, Holger; Ley, Klaus; Wolf, Dennis; Saliba, Antoine-Emmanuel; Zernecke, Alma in Circulation Research (2018). CIRCRESAHA.117.312509.
    • {CRISPR} {RNA}-{Dependent} {Binding} and {Cleavage} of {Endogenous} {RNAs} by the {Campylobacter} jejuni {Cas}9. Dugar, Gaurav; Leenay, Ryan T.; Eisenbart, Sara K.; Bischler, Thorsten; Aul, Belinda U.; Beisel, Chase L.; Sharma, Cynthia M. in Molecular Cell (2018). 69(5) 893–905.e7.
    • {hnRNP} {R} and its main interactor, the noncoding {RNA} 7SK, coregulate the axonal transcriptome of motoneurons. Briese, Michael; Saal-Bauernschubert, Lena; Ji, Changhe; Moradi, Mehri; Ghanawi, Hanaa; Uhl, Michael; Appenzeller, Silke; Backofen, Rolf; Sendtner, Michael in Proceedings of the National Academy of Sciences (2018). 115(12) E2859-E2868.
    • A {Novel} {Mechanism} of {Inactivating} {Antibacterial} {Nitro} {Compounds} in the {Human} {Pathogen} {Staphylococcus} aureus by {Overexpression} of a {NADH}-{Dependent} {Flavin} {Nitroreductase}. El-Hossary, Ebaa M.; Förstner, Konrad U.; François, Patrice; Baud, Damien; Streker, Karin; Schrenzel, Jacques; Ohlsen, Knut; Holzgrabe, Ulrike in Antimicrobial Agents and Chemotherapy (2018). 62(2) e01510–17.
    • Explorative results from multistep screening for potential genetic risk loci of Alzheimer’s disease in the longitudinal VITA study cohort. Scholz, Claus-J{\"u}rgen; Weber, Heike; Jungwirth, Susanne; Danielczyk, Walter; Reif, Andreas; Tragl, Karl-Heinz; Fischer, Peter; Riederer, Peter; Deckert, J{\"u}rgen; Gr{\"u}nblatt, Edna in Journal of Neural Transmission (2018). 125(1) 77–87.
    2017[ to top ]
    • {sRNA}154 a newly identified regulator of nitrogen fixation in {Methanosarcina} mazei strain {Gö}1. Prasse, Daniela; Förstner, Konrad U.; Jäger, Dominik; Backofen, Rolf; Schmitz, Ruth A. in RNA Biology (2017). 14(11) 1544–1558.
    • Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis. van Hulzen, Kimm J.E.; Scholz, Claus J.; Franke, Barbara; Ripke, Stephan; Klein, Marieke; McQuillin, Andrew; Sonuga-Barke, Edmund J.; Kelsoe, John R.; Land{\’{e}}n, Mikael; Andreassen, Ole A.; Lesch, Klaus-Peter; Weber, Heike; Faraone, Stephen V.; Arias-Vasquez, Alejandro; Reif, Andreas in Biological Psychiatry (2017). 82(9) 634–641.
    • Insights into {Microalga} and {Bacteria} {Interactions} of {Selected} {Phycosphere} {Biofilms} {Using} {Metagenomic}, {Transcriptomic}, and {Proteomic} {Approaches}. Krohn-Molt, Ines; Alawi, Malik; Förstner, Konrad U.; Wiegandt, Alena; Burkhardt, Lia; Indenbirken, Daniela; Thieß, Melanie; Grundhoff, Adam; Kehr, Julia; Tholey, Andreas; Streit, Wolfgang R. in Frontiers in Microbiology (2017). 8
    • Insights into Microalga and Bacteria Interactions of Selected Phycosphere Biofilms Using Metagenomic, Transcriptomic, and Proteomic Approaches. Krohn-Molt, Ines; Alawi, Malik; Förstner, Konrad U.; Wiegandt, Alena; Burkhardt, Lia; Indenbirken, Daniela; Thie{\ss}, Melanie; Grundhoff, Adam; Kehr, Julia; Tholey, Andreas; Streit, Wolfgang R. in Frontiers in Microbiology (2017). 8
    • {GT}‐rich promoters can drive {RNA} pol {II} transcription and deposition of {H}2A.{Z} in {African} trypanosomes. Wedel, Carolin; Förstner, Konrad U.; Derr, Ramona; Siegel, T. Nicolai in The EMBO Journal (2017). 36(17) 2581–2594.
    • Hypermethylation of the non-imprinted maternal MEG3 and paternal MEST alleles is highly variable among normal individuals. Haertle, Larissa; Maierhofer, Anna; Böck, Julia; Lehnen, Harald; Böttcher, Yvonne; Blüher, Matthias; Schorsch, Martin; Potabattula, Ramya; El Hajj, Nady; Appenzeller, Silke; Haaf, Thomas in PLOS ONE (2017). 12(8) 1–16.
    • The regulation of tetraspanin 8 gene expression—{A} potential new mechanism in the pathogenesis of bipolar disorder. Schartner, Christoph; Scholz, Claus-Jürgen; Weber, Heike; Post, Antonia; Freudenberg, Florian; Grünewald, Lena; Reif, Andreas in American Journal of Medical Genetics Part B: Neuropsychiatric Genetics (2017). 174(7) 740–750.
    • The enteric nervous system is a potential autoimmune target in multiple sclerosis. Wunsch, Marie; Jabari, Samir; Voussen, Barbara; Enders, Michael; Srinivasan, Shanthi; Cossais, François; Wedel, Thilo; Boettner, Martina; Schwarz, Anna; Weyer, Linda; Göcer, Oktay; Schroeter, Michael; Maeurer, Mathias; Woenckhaus, Matthias; Pollok, Karolin; Radbruch, Helena; Klotz, Luisa; Scholz, Claus-Jürgen; Nickel, Joachim; Friebe, Andreas; Addicks, Klaus; Ergün, Süleyman; Lehmann, Paul V.; Kuerten, Stefanie in Acta Neuropathologica (2017). 134(2) 281–295.
    • The glucocorticoid receptor in monocyte-derived macrophages is critical for cardiac infarct repair and remodeling. Galuppo, Paolo; Vettorazzi, Sabine; Hövelmann, Julian; Scholz, Claus-Jürgen; Tuckermann, Jan Peter; Bauersachs, Johann; Fraccarollo, Daniela in The FASEB Journal (2017). 31(11) 5122–5132.
    • An {RpoHI}-{Dependent} {Response} {Promotes} {Outgrowth} after {Extended} {Stationary} {Phase} in the {Alphaproteobacterium} {Rhodobacter} sphaeroides. Remes, B.; Rische-Grahl, T.; Müller, K. M. H.; Förstner, K. U.; Yu, Sung-Huan; Weber, L.; Jäger, A.; Peuser, V.; Klug, G. in Journal of Bacteriology (2017). 199(14) e00249–17.
    • Differential effects of {FTY}720 on the {B} cell compartment in a mouse model of multiple sclerosis. Bail, Kathrin; Notz, Quirin; Rovituso, Damiano M.; Schampel, Andrea; Wunsch, Marie; Koeniger, Tobias; Schropp, Verena; Bharti, Richa; Scholz, Claus-Juergen; Foerstner, Konrad U.; Kleinschnitz, Christoph; Kuerten, Stefanie in Journal of Neuroinflammation (2017). 14 148.
    • {dRNA}-seq transcriptional profiling of the {FK}506 biosynthetic gene cluster in Streptomyces tsukubaensis {NRRL}18488 and general analysis of the transcriptome. Bauer, Judith S.; Fillinger, Sven; Förstner, Konrad; Herbig, Alexander; Jones, Adam C.; Flinspach, Katrin; Sharma, Cynthia; Gross, Harald; Nieselt, Kay; Apel, Alexander K. in {RNA} Biology (2017). 14(11) 1617–1626.
    • {APRICOT}: an integrated computational pipeline for the sequence-based identification and characterization of {RNA}-binding proteins. Sharan, Malvika; Förstner, Konrad U.; Eulalio, Ana; Vogel, Jörg in Nucleic Acids Research (2017). 45(11) e96-e96.
    • Nimodipine fosters remyelination in a mouse model of multiple sclerosis and induces microglia-specific apoptosis. Schampel, Andrea; Volovitch, Oleg; Koeniger, Tobias; Scholz, Claus-Jürgen; Jörg, Stefanie; Linker, Ralf A.; Wischmeyer, Erhard; Wunsch, Marie; Hell, Johannes W.; Ergün, Süleyman; Kuerten, Stefanie in Proceedings of the National Academy of Sciences (2017). 114(16) E3295-E3304.
    • Pan-{Raf} co-operates with {PI}3K-dependent signalling and critically contributes to myeloma cell survival independently of mutated {RAS}. Müller, E.; Bauer, S.; Stühmer, T.; Mottok, A.; Scholz, C.-J.; Steinbrunn, T.; Brünnert, D.; Brandl, A.; Schraud, H.; Kreßmann, S.; Beilhack, A.; Rosenwald, A.; Bargou, R. C.; Chatterjee, M. in Leukemia (2017). 31(4) 922–933.
    • Transcription {Profiling} of {Bacillus} subtilis {Cells} {Infected} with {AR}9, a {Giant} {Phage} {Encoding} {Two} {Multisubunit} {RNA} {Polymerases}. Lavysh, Daria; Sokolova, Maria; Slashcheva, Marina; Förstner, Konrad U.; Severinov, Konstantin in mBio (2017). 8(1) e02041–16.
    • In {Vivo} {Cleavage} {Map} {Illuminates} the {Central} {Role} of {RNase} {E} in {Coding} and {Non}-coding {RNA} {Pathways}. Chao, Yanjie; Li, Lei; Girodat, Dylan; Förstner, Konrad U.; Said, Nelly; Corcoran, Colin; Śmiga, Michał; Papenfort, Kai; Reinhardt, Richard; Wieden, Hans-Joachim; Luisi, Ben F.; Vogel, Jörg in Molecular Cell (2017). 65(1) 39–51.