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    Open PhD Student Position

     

    A PhD student position is available for a highly motivated individual in the IZKF (Interdisciplinary Center for Clinical Research) Research Group “Tissue Regeneration in Musculoskeletal Diseases” led by Dr. Marietta Herrmann. The group was founded in 2017 and is affiliated with the Bernhard-Heine-Center for Locomotion Research and part of the Musculoskeletal Center Würzburg (MCW), an interdisciplinary network focussing on disease-oriented research in the field of musculoskeletal diseases. In close collaboration with the other MCW members, the emphasis of the group is put on basic research into regenerative mechanisms and the development of innovative cell therapies for musculoskeletal tissue repair, with a special focus on Mesenchymal Stromal Cells (MSC).

    The PhD position is available within an international consortium, with academic and industry partners from Germany and Serbia, focusing on new therapeutic strategies for reconstruction of bone defects. The PhD project will involve the characterization of cellular and soluble components of human bone autografts, the application of 3D cell culture techniques and the identification of novel strategies for boosting the regenerative potential of the graft material in close interaction with the collaboration partners... more
     



    Open PhD Student Position

    A PhD student position is available for a highly motivated individual in the IZKF (Interdisciplinary Center for Clinical Research) Research Group “Tissue Regeneration in Musculoskeletal Diseases” led by Dr. Marietta Herrmann. The group was founded in 2017 and is affiliated with the Bernhard-Heine-Center for Locomotion Research and part of the Musculoskeletal Center Würzburg (MCW), an interdisciplinary network focussing on disease-oriented research in the field of musculoskeletal diseases. In close collaboration with the other MCW members, the emphasis of the group is put on basic research into regenerative mechanisms and the development of innovative cell therapies for musculoskeletal tissue repair, with a special focus on Mesenchymal Stromal Cells (MSC).

    The PhD project will focus on unravelling molecular mechanisms of the rare disease Primary Failure of Eruption (PFE), which is characterized by incomplete tooth eruption and associated with mutations in the parathyroid hormone receptor (PTH1R). Aim of the collaborative project with the orthodontic department (Prof. Martin Eigenthaler) is to apply genome editing strategies, such as CRISPR/Cas9, to generate transgenic cell lines to investigate functional consequences of PTH1R deficiency and to test potential novel therapeutic strategies... more