Intern

AG Becker

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Stem cells are fascinating cell types both for basic research as well as for clinical applications.
The Becker group is analyzing the developmental potential and molecular regulators of pluri-
and multipotent stem cells.

Current Publications AG Becker

KDM6A, a histone demethylase, regulates stress hematopoiesis and early B-cell differentation. Sascha Huppertz, Katharina Senger, Andreas Brown, Hanna Leins, Karina Eiwen, Madhanie A Mulaw, Hartmut Geiger, Matthias Becker. Exp Hematol. 2021 Jun 12; S0301-472X(21) Online ahead of print.

The miR-26 family regulates neural differentiation-associated microRNAs and mRNAs by directly targeting REST. Mark Sauer, Nina Was, Thomas Ziegenhals, Xiantao Wang, Markus Hafner, Matthias Becker, Utz Fischer. J Cell Sci. 2021 May 20; doi.org/10.1242/jcs.257535.

Ischemia-Like Stress Conditions Stimulate Trophic Activities of Adipose-Derived Stromal/Stem Cells. Julia Bachmann, Elias Ehlert, Matthias Becker, Christoph Otto, Katrin Radeloff, Torsten Blunk and Petra Bauer-Kreisel. Cells. 2020 Aug 21;9(9):E1935. doi: 10.3390/cells9091935.

Human Adipose-Derived Mesenchymal Stromal/Stem Cell Spheroids Possess High Adipogenic Capacity and Acquire an Adipose Tissue-like Extracellular Matrix Pattern.
Hoefner C, Muhr C, Horder H, Wiesner M, Wittmann K, Lukaszyk D, Radeloff K, Winnefeld M, Becker M, Blunk T, Bauer-Kreisel P.Tissue Eng Part A 2020 Apr 9. doi: 10.1089/ten.

Polycomb Protein BMI1 Regulates Osteogenic Differentiation of Human Adipose Tissue-Derived Mesenchymal Stem Cells Downstream of GSK3. Becker Matthias, Potapenko Tamara, Niklaus Andrea, Bieback Karen, Ho Anthony, Müller Albrecht. Stem Cells Dev. 2016 Jun 15;25(12): 922-33.

Inhibition of KDM6 activity during murine ES cell differentiation induces DNA damage. Christine Hofstetter, Justyna M. Kampka, Sascha Huppertz, Heike Weber, Andreas Schlosser, Albrecht M. Müller, Matthias Becker, J Cell Sci 2016 : doi: 10.1242 /jcs. 175174.

Pcgf6, a polycomb group protein, regulates mesodermal lineage differentiation in murine ES cells and functions in iPS reprogramming. Zdzieblo, D., Li, X., Lin, Q., Zenke, M., Illich, D.J., Becker, M. and Müller, A.M. Stem Cells, (2014).