Originalarbeiten

• Shirley AJ., Schweeberg S., Waag T., Peindl M., Dandekar G., Walles H., Jakob F., Krueger A., Ebert R. (2021) The influence of differently functionalized nanodiamonds on proliferation, apoptosis and EMT/MET phenomena in 2D and 3D tumor cell cultures, J Mater Chem B, 9, 9395-9405.
• Altmann S., Mut J., Wolf N., Meißner-Weigl J., Rudert M., Jakob F., Gutmann M., Lühmann T., Seibel J., Ebert R. (2021) Metabolic glycoengineering in hMSC-TERT cells as a model for skeletal precursors by using modified azide/alkyne mono-saccharides. Int J Mol Sci. 22(6), 2820. doi:10.3390/ijms22062820
• Brandl A., Solimando AG., Mokhtari Z.,1, Tabares P., Medler J., Manz H., Da Via M., Croci GA., Kurzwart M., Thusek S., Schneider T., Ebert R., Jakob F., Einsele H., Beilhack A. (2021) Junctional Adhesion Molecule-C expression specifies a CD138low/neg multiple myeloma cell population in mice and men, Blood Adv. 2021 Dec 3:bloodadvances.2021004354. doi: 10.1182/bloodadvances.2021004354
• Ebert R, Weissenberger M, Braun C, Wagenbrenner M, Herrmann M, Müller-Deubert S, Krug M, Jakob F, Rudert M. Impaired regenerative capacity and senescence-associated secretory phenotype in mesenchymal stromal cells from samples of patients with aseptic joint arthroplasty loosening. J Orthop Res. 2021 Mar 22. doi: 10.1002/jor.25041. Epub ahead of print. PMID: 33749912.

• Ohlebusch B, Borst A, Frankenbach T, Klopocki E, Jakob F, Liedtke D, Graser S. Investigation of alpl expression and Tnap-activity in zebrafish implies conserved functions during skeletal and neuronal development. Sci Rep. 2020 Aug 7;10(1):13321. doi: 10.1038/s41598-020-70152-5
• Müller-Deubert S, Ege C, Krug M, Meißner-Weigl J, Rudert M, Bischof O, Jakob F, Ebert R. Phosphodiesterase 10A Is a Mediator of Osteogenic Differentiation and Mechanotransduction in Bone Marrow-Derived Mesenchymal Stromal Cells. Stem Cells Int. 2020 Jun 6;2020:7865484. doi: 10.1155/2020/7865484. eCollection 2020.
• Kemmler W, Kohl M, Fröhlich M, Jakob F, Engelke K, von Stengel S, Schoene D. Effects of High Intensity Resistance Training on Osteopenia and Sarcopenia parameters in Older Men with Osteosarcopenia - One-year results of the randomized controlled Franconian Osteopenia and Sarcopenia Trial (FrOST). J Bone Miner Res. 2020 Apr 9. doi: 10.1002/jbmr.4027. [Epub ahead of print]
• Melms H, Herrmann M, Förstner K, Bharti R, Schneider D, Mentrup B, Rudert M, Schlagenhauf U, Jakob F, Graser S. Novel molecular cues for dental defects in hypophosphatasia. Exp Cell Res. 2020 Apr 22:112026. doi: 10.1016/j.yexcr.2020.112026. [Epub ahead of print]
• Pereira AR, Rudert M, Herrmann M. Decellularized human bone as a 3D model to study skeletal progenitor cells in a natural environment. Methods Cell Biol. 2020;157:123-141. doi: 10.1016/bs.mcb.2019.11.018. Epub 2019 Dec 31.
• Rueckl K, Liebich A, Bechler U, Springer B, Rudert M, Boettner F. Return to sports after hip resurfacing versus total hip arthroplasty: a mid-term case control study. Arch Orthop Trauma Surg. 2020 Apr 15. doi: 10.1007/s00402-020-03414-6. [Epub ahead of print]
• Horas K, Hoffmann R, Faulenbach M, Heinz SM, Langheinrich A, Schweigkofler U. Advances in the Preoperative Planning of Revision Trauma Surgery Using 3D Printing Technology. J Orthop Trauma. 2020 May;34(5):e181-e186. doi: 10.1097/BOT.0000000000001708.
• Wagenbrenner M, Heinz T, Horas K, Jakuscheit A, Arnholdt J, Herrmann M, Rudert M, Holzapfel BM, Steinert AF, Weißenberger M. The human arthritic hip joint is a source of mesenchymal stromal cells (MSCs) with extensive multipotent differentiation potential. BMC Musculoskelet Disord. 2020 May 13;21(1):297. doi: 10.1186/s12891-020-03340-z.
• Weißenberger M, Petersen N, Bölch S, Rak D, Arnholdt J, Rudert M, Holzapfel BM. Revision of unicompartmental knee arthroplasty using the in situ referencing technique. Oper Orthop Traumatol. 2020 Mar 5. doi: 10.1007/s00064-020-00656-w. [Epub ahead of print]
• Weissenberger M, Weissenberger MH, Gilbert F, Groll J, Evans CH, Steinert AF. Reduced hypertrophy in vitro after chondrogenic differentiation of adult human mesenchymal stem cells following adenoviral SOX9 gene delivery. BMC Musculoskelet Disord. 2020 Feb 17;21(1):109. doi: 10.1186/s12891-020-3137-4.
• Chaudry O, Grimm A, Friedberger A, Kemmler W, Uder M, Jakob F, Quick HH, von Stengel S, Engelke K. Magnetic Resonance Imaging and Bioelectrical Impedance Analysis to Assess Visceral and Abdominal Adipose Tissue. Obesity (Silver Spring). 2020 Feb;28(2):277-283. doi: 10.1002/oby.22712. Epub 2020 Jan 3.
• Zeiter S, Koschitzki K, Alini M, Jakob F, Rudert M, Herrmann M. Evaluation of Preclinical Models for the Testing of Bone Tissue-Engineered Constructs. Tissue Eng Part C Methods. 2020 Jan 13. doi: 10.1089/ten.TEC.2019.0213. [Epub ahead of print]
• Weißenberger M, Heinz T, Boelch SP, Niemeyer P, Rudert M, Barthel T, Reppenhagen S. Is debridement beneficial for focal cartilage defects of the knee: data from the German Cartilage Registry (KnorpelRegister DGOU). Arch Orthop Trauma Surg. 2020 Jan 22. doi: 10.1007/s00402-020-03338-1. [Epub ahead of print]

• Prager P, Schieker M, Jakob F, Docheva D, Konrads C, Steinert A. Characterization of human telomerase reverse transcriptase immortalized anterior cruciate ligament cell lines. Biomed J. 2019 Dec;42(6):371-380. doi: 10.1016/j.bj.2019.05.005. Epub 2019 Dec 23.
• Zeiter S, Koschitzki K, Alini M PhD, Jakob F, Rudert M, Herrmann M. Evaluation of preclinical models for the testing of bone tissue engineered constructs. Tissue Eng Part C Methods. 2019 Dec 6. doi: 10.1089/ten.TEC.2019.0213. [Epub ahead of print]
• Herrmann M, Hildebrand M, Menzel U, Fahy N, Alini M, Lang S, Benneker L, Verrier S, Stoddart MJ, Bara JJ. Phenotypic Characterization of Bone Marrow Mononuclear Cells and Derived Stromal Cell Populations from Human Iliac Crest, Vertebral Body and Femoral Head. Int J Mol Sci. 2019 Jul 14;20(14). pii: E3454. doi: 10.3390/ijms20143454.
• Kremer A, Wußmann M, Herrmann M, Raghunath M, Walles H. Ciclopirox olamine promotes the angiogenic response of endothelial cells and mesenchymal stem cells. Clin Hemorheol Microcirc. 2019;73(2):317-328. doi: 10.3233/CH-190559.
• Pereira AR, Trivanović D, Herrmann M. Approaches to mimic the complexity of the skeletal mesenchymal stem/stromal cell niche in vitro. Eur Cell Mater. 2019 Feb 11;37:88-112. doi: 10.22203/eCM.v037a07. Review.
• Schmalzl J, Plumhoff P, Gilbert F, Gohlke F, Konrads C, Brunner U, Jakob F, Ebert R, Steinert AF. Tendon-derived stem cells from the long head of the biceps tendon: Inflammation does not affect the regenerative potential. Bone Joint Res. 2019 Oct 3;8(9):414-424. doi: 10.1302/2046-3758.89.BJR-2018-0214.R2. eCollection 2019 Sep.
• Schierjott RA, Hettich G, Graichen H, Jansson V, Rudert M, Traina F, Weber P, Grupp TM. Quantitative assessment of acetabular bone defects: A study of 50 computed tomography data sets. PLoS One. 2019 Oct 17;14(10):e0222511. doi: 10.1371/journal.pone.0222511. eCollection 2019.
• Rueckl K, Ernstbrunner L, Reichel T, Bouaicha S, Barthel T, Rudert M, Plumhoff P. [Indications and techniques of arthroscopic anterior and lateral acromioplasty]. Oper Orthop Traumatol. 2019 Aug;31(4):351-370. doi: 10.1007/s00064-019-0620-x. Epub 2019 Jul 30. German.
• Wagner F, Maderbacher G, Matussek J, Holzapfel BM, Kammer B, Hubertus J, Anders S, Winkler S, Grifka J, Keshmiri A. A Knee Size-Independent Parameter for Malalignment of the Distal Patellofemoral Joint in Children. Adv Orthop. 2019 Sep 15;2019:3496936. doi: 10.1155/2019/3496936. eCollection 2019.
• Fraissler L, Boelch SP, Schäfer T, Walcher M, Arnholdt J, Maier G, Jakob F, Rudert M, Horas K. Vitamin D Deficiency in Patients With Idiopathic and Traumatic Osteochondritis Dissecans of the Talus. Foot Ankle Int. 2019 Nov;40(11):1309-1318. doi: 10.1177/1071100719864325. Epub 2019 Aug 2.
• Reichel T, Rueckl K, Fenwick A, Vogt N, Rudert M, Plumhoff P. Hibernoma of the Upper Extremity: Complete Case of a Rare but Benign Soft Tissue Tumor. Case Rep Orthop. 2019 May 21;2019:6840693. doi: 10.1155/2019/6840693. eCollection 2019.
• Beckmann J, Steinert AF, Huber B, Rudert M, Köck FX, Buhs M, Rolston L. Customised bi-compartmental knee arthroplasty shows encouraging 3-year results: findings of a prospective, multicenter study. Knee Surg Sports Traumatol Arthrosc. 2019 Jun 28. doi: 10.1007/s00167-019-05595-z. [Epub ahead of print]
• Lahr CA, Wagner F, Shafiee A, Rudert M, Hutmacher DW, Holzapfel BM. Recombinant Human Bone Morphogenetic Protein 7 Exerts Osteo-Catabolic Effects on Bone Grafts That Outweigh Its Osteo-Anabolic Capacity. Calcif Tissue Int. 2019 Sep;105(3):331-340. doi: 10.1007/s00223-019-00574-5. Epub 2019 Jun 18.
• Grimm A, Nickel MD, Chaudry O, Uder M, Jakob F, Kemmler W, Quick HH, Engelke K. Feasibility of Dixon magnetic resonance imaging to quantify effects of physical training on muscle composition-A pilot study in young and healthy men. Eur J Radiol. 2019 May;114:160-166. doi: 10.1016/j.ejrad.2019.03.019. Epub 2019 Mar 26.
• Reppenhagen S, Weißenberger M, Barthel T, Rudert M, Anetzberger H. [Virtual arthroscopy : Gaming or training concept of the future]. Unfallchirurg. 2019 Jun;122(6):431-438. doi: 10.1007/s00113-019-0653-5. Review. German.
• Fraissler L, Horas K, Bölch S, Raab P, Rudert M, Walcher M. Extensor hallucis longus-transfer for tibialis anterior tendon rupture repair. Oper Orthop Traumatol. 2019 Apr;31(2):143-148. doi: 10.1007/s00064-018-0571-7. Epub 2018 Oct 9. Review.
• Ziouti F, Ebert R, Rummler M, Krug M, Müller-Deubert S, Lüdemann M, Jakob F, Willie BM, Jundt F. NOTCH Signaling Is Activated through Mechanical Strain in Human Bone Marrow-Derived Mesenchymal Stromal Cells. Stem Cells Int. 2019 Feb 26;2019:5150634. doi: 10.1155/2019/5150634. eCollection 2019.
• Frey SP, Yorumazel B, Hölscher-Doht S, Eden L, Schütze N, Meffert RH, Jansen H. CYR61 improves muscle force recreation in a rabbit trauma model. Technol Health Care. 2019 Mar 14. doi: 10.3233/THC-191635. [Epub ahead of print]
• Tylek T, Schilling T, Schlegelmilch K, Ries M, Rudert M, Jakob F, Groll J. Platelet lysate outperforms FCS and human serum for co-culture of primary human macrophages and hMSCs. Sci Rep. 2019 Mar 5;9(1):3533. doi: 10.1038/s41598-019-40190-9.
• Schmalzl J, Plumhoff P, Gilbert F, Gohlke F, Konrads C, Brunner U, Jakob F, Ebert R, Steinert AF. The inflamed biceps tendon as a pain generator in the shoulder: A histological and biomolecular analysis. J Orthop Surg (Hong Kong). 2019 Jan-Apr;27(1):2309499018820349. doi: 10.1177/2309499018820349.
• Högler W, Langman C, Gomes da Silva H, Fang S, Linglart A, Ozono K, Petryk A, Rockman-Greenberg C, Seefried L, Kishnani PS. Diagnostic delay is common among patients with hypophosphatasia: initial findings from a longitudinal, prospective, global registry. BMC Musculoskelet Disord. 2019 Feb 14;20(1):80.doi: 10.1186/s12891-019-2420-8.
• Boelch SP, Jordan MC, Arnholdt J, Steinert AF, Rudert M, Luedemann M. Antibiotic elution and compressive strength of gentamicin/vancomycin loaded bone cements are considerably influenced by immersion fluid volume. J Mater Sci Mater Med. 2019 Feb 14;30(2):29. doi: 10.1007/s10856-019-6229-7.
• Wagner F, Holzapfel BM, Martine LC, McGovern J, Lahr CA, Boxberg M, Prodinger PM, Grässel S, Loessner D, Hutmacher DW. A humanized bone microenvironment uncovers HIF2 alpha as a latent marker for osteosarcoma. Acta Biomater. 2019 Apr 15;89:372-381. doi: 10.1016/j.actbio.2019.02.051. Epub 2019 Mar 2.

• Weis M, Shan J, Kuhlmann M, Jungst T, Tessmar J, Groll J. Evaluation of Hydrogels Based on Oxidized Hyaluronic Acid for Bioprinting. Gels. 2018 Oct 9;4(4). pii: E82. doi: 10.3390/gels4040082.
• Lang S, Loibl M, Herrmann M. Platelet-Rich Plasma in Tissue Engineering: Hype and Hope. Eur Surg Res. 2018;59(3-4):265-275. doi: 10.1159/000492415. Epub 2018 Sep 21. Review.
• Boelch SP, Jakuscheit A, Doerries S, Fraissler L, Hoberg M, Arnholdt J, Rudert M. Periprosthetic infection is the major indication for TKA revision - experiences from a university referral arthroplasty center. BMC Musculoskelet
  Disord. 2018 Nov 10;19(1):395. doi: 10.1186/s12891-018-2314-1.
• Boelch SP, Rueckl K, Fuchs C, Jordan M, Knauer M, Steinert A, Rudert M, Luedemann M. Comparison of Elution Characteristics and Compressive Strength of Biantibiotic-Loaded PMMA Bone Cement for Spacers: Copal® Spacem with Gentamicin
  and Vancomycin versus Palacos® R+G with Vancomycin. Biomed Res Int. 2018 Oct 16;2018:4323518. doi: 10.1155/2018/4323518. eCollection 2018.
• Arnholdt J, Kamawal Y, Holzapfel BM, Ripp A, Rudert M, Steinert AF. Evaluation of implant fit and frontal plane alignment after bi-compartmental knee arthroplasty using patient-specific instruments and implants. Arch Med Sci. 2018 Oct;14(6):1424-1431. doi: 10.5114/aoms.2018.79007. Epub 2018 Oct 23.
• Loessner D, Rockstroh A, Shokoohmand A, Holzapfel BM, Wagner F, Baldwin J, Boxberg M, Schmalfeldt B, Lengyel E, Clements JA, Hutmacher DW. A 3D tumor microenvironment regulates cell proliferation, peritoneal growth and expression patterns. Biomaterials. 2019 Jan;190-191:63-75. doi: 10.1016/j.biomaterials.2018.10.014. Epub 2018 Oct 16.
• McGovern JA, Shafiee A, Wagner F, Lahr CA, Landgraf M, Meinert C, Williams ED, Russell PJ, Clements JA, Loessner D, Holzapfel BM, Risbridger GP, Hutmacher DW. Humanization of the Prostate Microenvironment Reduces Homing of PC3 Prostate Cancer Cells to Human Tissue-Engineered Bone. Cancers (Basel). 2018 Nov 13;10(11). pii: E438. doi: 10.3390/cancers10110438.
• Konrads C, Franz A, Hoberg M, Rudert M. Similar Outcomes of Two-Stage Revisions for Infection and One-Stage Revisions for Aseptic Revisions of Knee Endoprostheses. J Knee Surg. 2019 Sep;32(9):897-899. doi: 10.1055/s-0038-1670627. Epub 2018 Sep 7.
• Dondossola E, Alexander S, Holzapfel BM, Filippini S, Starbuck MW, Hoffman RM, Navone N, De-Juan-Pardo EM, Logothetis CJ, Hutmacher DW, Friedl P. Intravital microscopy of osteolytic progression and therapy response of cancer lesions in the bone. Sci Transl Med. 2018 Aug 1;10(452). pii: eaao5726. doi: 10.1126/scitranslmed.aao5726.
• Hafen B, Wiesner S, Schlegelmilch K, Keller A, Seefried L, Ebert R, Walles H, Jakob F, Schütze N. Physical contact between mesenchymal stem cells and endothelial precursors induces distinct signatures with relevance to the very early phase of regeneration. J Cell Biochem. 2018 Nov;119(11):9122-9140. doi: 10.1002/jcb.27175. Epub 2018 Aug 13.
• Reichert JC, von Rottkay E, Roth F, Renz T, Hausmann J, Kranz J, Rackwitz L, Nöth U, Rudert M. A prospective randomized comparison of the minimally invasive direct anterior and the transgluteal approach for primary total hip arthroplasty. BMC Musculoskelet Disord. 2018 Jul 19;19(1):241. doi: 10.1186/s12891-018-2133-4.
• Thiele S, Zimmer A, Göbel A, Rachner TD, Rother S, Fuessel S, Froehner M, Wirth MP, Muders MH, Baretton GB, Jakob F, Rauner M, Hofbauer LC. Role of WNT5A receptors FZD5 and RYK in prostate cancer cells. Oncotarget. 2018 Jun 5;9(43):27293-27304. doi: 10.18632/oncotarget.25551. eCollection 2018 Jun 5.
• Boelch SP, Roth M, Arnholdt J, Rudert M, Luedemann M. Synovial Fluid Aspiration Should Not Be Routinely Performed during the Two-Stage Exchange of the Knee. Biomed Res Int. 2018 Jun 12;2018:6720712. doi: 10.1155/2018/6720712. eCollection 2018.
• Walcher MG, Fraissler L, Konrads C, Plumhoff P, Hoberg M, Rudert M. [Osteotomies of the distal tibia]. Oper Orthop Traumatol. 2018 Aug;30(4):253-275. doi: 10.1007/s00064-018-0555-7. Epub 2018 Jun 22. German.
• Lüdemann M, Munoz P, Wagner M, Malzahn U, Horas K, Heuschmann P, Rudert M. The Effect of Antiseptics in the Prophylaxis of Infection in Orthopaedic Surgery. Z Orthop Unfall. 2018 Oct;156(5):567-573. doi: 10.1055/a-0608-5292. Epub 2018 Jun 14.
• Konrads C, Jovic S, Rueckl K, Fenwick A, Barthel T, Rudert M, Plumhoff P. Surgical technique and clinical outcome of arthroscopic shoulder stabilization via suture anchors using the lasso-loop stitch. J Orthop. 2018 May 7;15(2):553-557. doi: 10.1016/j.jor.2018.05.023. eCollection 2018 Jun.
• Boelch SP, Arnholdt J, Holzapfel BM, Jakuscheit A, Rudert M, Hoberg M. Revision knee arthroplasty with rotating hinge systems in patients with gross ligament instability. Int Orthop. 2018 Dec;42(12):2825-2833. doi: 10.1007/s00264-018-3982-z. Epub 2018 May 22.
• Genest F, Seefried L. Subtrochanteric and diaphyseal femoral fractures in hypophosphatasia-not atypical at all. Osteoporos Int. 2018 Aug;29(8):1815-1825. doi: 10.1007/s00198-018-4552-3. Epub 2018 May 17.
• Adam C, Glück L, Ebert R, Goebeler M, Jakob F, Schmidt M. The MEK5/ERK5 mitogen-activated protein kinase cascade is an effector pathway of bone-sustaining bisphosphonates that regulates osteogenic differentiation and mineralization. Bone. 2018 Jun;111:49-58. doi: 10.1016/j.bone.2018.03.020. Epub 2018 Mar 19.
• Prager P, Kunz M, Ebert R, Klein-Hitpass L, Sieker J, Barthel T, Jakob F, Konrads C, Steinert A. Mesenchymal Stem Cells Isolated from the Anterior Cruciate Ligament: Characterization and Comparison of Cells from Young and Old Donors. Knee Surg Relat Res. 2018 Sep 1;30(3):193-205. doi: 10.5792/ksrr.17.067.
• Solimando AG, Brandl A, Mattenheimer K, Graf C, Ritz M, Ruckdeschel A, StühmerT, Mokhtari Z, Rudelius M, Dotterweich J, Bittrich M, Desantis V, Ebert R,Trerotoli P, Frassanito MA, Rosenwald A, Vacca A, Einsele H, Jakob F, Beilhack A.JAM-A as a prognostic factor and new therapeutic target in multiple myeloma.Leukemia. 2018 Mar;32(3):736-743. doi: 10.1038/leu.2017.287. Epub 2017 Sep 28.
• Fernandez-Rebollo E, Eipel M, Seefried L, Hoffmann P, Strathmann K, Jakob F,Wagner W. Primary Osteoporosis Is Not Reflected by Disease-Specific DNA Methylation or Accelerated Epigenetic Age in Blood. J Bone Miner Res. 2018 Feb;33(2):356-361. doi: 10.1002/jbmr.3298. Epub 2017 Oct 23. 
• Boelch SP, Weissenberger M, Spohn F, Rudert M, Luedemann M. Insufficientsensitivity of joint aspiration during the two-stage exchange of the hip withspacers. J Orthop Surg Res. 2018 Jan 10;13(1):7. doi: 10.1186/s13018-017-0703-z. 
• Rossnagl S, Ghura H, Groth C, Altrock E, Jakob F, Schott S, Wimberger P, Link T, Kuhlmann JD, Stenzl A, Hennenlotter J, Todenhöfer T, Rojewski M, Bieback K,Nakchbandi IA. A Subpopulation of Stromal Cells Controls Cancer Cell Homing tothe Bone Marrow. Cancer Res. 2018 Jan 1;78(1):129-142. doi:10.1158/0008-5472.CAN-16-3507. Epub 2017 Oct 24.

• de Ruijter M, Hrynevich A, Haigh JN, Hochleitner G, Castilho M, Groll J, Malda J, Dalton PD. Out-of-Plane 3D-Printed Microfibers Improve the Shear Properties of Hydrogel Composites. Small. 2018 Feb;14(8). doi: 10.1002/smll.201702773. Epub 2017 Dec 14.
• Neshkova I, Meffert RH. Pilon Fractures of the Base of the Proximal Phalanx:Direct Intraosseous Joint Reduction with Bone-Grafting and Mini-Screws: A Case Report. JBJS Case Connect. 2017 Jan-Mar;7(1):e5. doi: 10.2106/JBJS.CC.16.00077.
• Jessberger S, Högger P, Genest F, Salter DM, Seefried L. Cellularpharmacodynamic effects of Pycnogenol® in patients with severe osteoarthritis: a randomized controlled pilot study. BMC Complement Altern Med. 2017 Dec16;17(1):537. doi: 10.1186/s12906-017-2044-1. 
• Seefried L, Genest F, Luksche N, Schneider M, Fazeli G, Brandl M, Bahner U, A Heidland A. Efficacy and safety of whole body vibration in maintenancehemodialysis patients - A pilot study. J Musculoskelet Neuronal Interact. 2017Dec 1;17(4):268-274.
• Holzapfel NP, Shokoohmand A, Wagner F, Landgraf M, Champ S, Holzapfel BM,Clements JA, Hutmacher DW, Loessner D. Lycopene reduces ovarian tumor growth and intraperitoneal metastatic load. Am J Cancer Res. 2017 Jun 1;7(6):1322-1336.eCollection 2017.
• Martine LC, Holzapfel BM, McGovern JA, Wagner F, Quent VM, Hesami P, WunnerFM, Vaquette C, De-Juan-Pardo EM, Brown TD, Nowlan B, Wu DJ, Hutmacher CO, Moi D,Oussenko T, Piccinini E, Zandstra PW, Mazzieri R, Lévesque JP, Dalton PD,Taubenberger AV, Hutmacher DW. Engineering a humanized bone organ model in miceto study bone metastases. Nat Protoc. 2017 Apr;12(4):639-663. doi:10.1038/nprot.2017.002. Epub 2017 Mar 2.
• Fernandez-Rebollo E, Mentrup B, Ebert R, Franzen J, Abagnale G, Sieben T, Ostrowska A, Hoffmann P, Roux PF, Rath B, Goodhardt M, Lemaitre JM, Bischof O, Jakob F, Wagner W. Human Platelet Lysate versus Fetal Calf Serum: These Supplements Do Not Select for Different Mesenchymal Stromal Cells. Sci Rep. 2017 Jul 11;7(1):5132. doi: 10.1038/s41598-017-05207-1.
• Ramani-Mohan RK, Schwedhelm I, Finne-Wistrand A, Krug M, Schwarz T, Jakob F, Walles H, Hansmann J. Deformation strain is the main physical driver for skeletal precursors to undergo osteogenesis in earlier stages of osteogenic cell maturation. J Tissue Eng Regen Med. 2018 Mar;12(3):e1474-e1479. doi: 10.1002/term.2565. Epub 2017 Nov 10.
• Müller-Deubert S, Seefried L, Krug M, Jakob F, Ebert R. Epidermal growth factor as a mechanosensitizer in human bone marrow stromal cells. Stem Cell Res. 2017 Oct;24:69-76. doi: 10.1016/j.scr.2017.08.012. Epub 2017 Aug 18.
• Horas K, Maier G, Jakob F, Maus U, Kurth A, Jakuscheit A, Rudert M, Holzapfel BM. High Prevalence of Vitamin D Deficiency in Patients with Bone Tumors. Cancer Invest. 2017 Sep 14;35(8):562-568. doi: 10.1080/07357907.2017.1351985. Epub 2017 Aug 11.
• Kishnani PS, Rush ET, Arundel P, Bishop N, Dahir K, Fraser W, Harmatz P, Linglart A, Munns CF, Nunes ME, Saal HM, Seefried L, Ozono K. Monitoring guidance for patients with hypophosphatasia treated with asfotase alfa. Mol Genet Metab. 2017 Sep;122(1-2):4-17. doi: 10.1016/j.ymgme.2017.07.010. Epub 2017 Jul 25.
• Shafiee A, Baldwin JG, Patel J, Holzapfel BM, Fisk NM, Khosrotehrani K, Hutmacher DW. Fetal Bone Marrow-Derived Mesenchymal Stem/Stromal Cells Enhance Humanization and Bone Formation of BMP7 Loaded Scaffolds. Biotechnol J. 2017 Dec;12(12). doi: 10.1002/biot.201700414.
• von Rottkay E, Rackwitz L, Rudert M, Nöth U, Reichert JC. Function and activity after minimally invasive total hip arthroplasty compared to a healthy population. Int Orthop. 2018 Feb;42(2):297-302. doi: 10.1007/s00264-017-3541-z. Epub 2017 Jul 12.
• Fraissler L, Konrads C, Hoberg M, Rudert M, Walcher M. Treatment of halluxvalgus deformity. EFORT Open Rev. 2016 Aug 25;1(8):295-302. doi: 10.1302/2058-5241.1.000005. eCollection 2016 Aug.
• Mülek M, Seefried L, Genest F, Högger P. Distribution of Constituents andMetabolites of Maritime Pine Bark Extract (Pycnogenol(®)) into Serum, BloodCells, and Synovial Fluid of Patients with Severe Osteoarthritis: A RandomizedControlled Trial. Nutrients. 2017 Apr 28;9(5). pii: E443. doi: 10.3390/nu9050443.
• Arnholdt J, Gilbert F, Blank M, Papazoglou J, Rudert M, Nöth U, Steinert AF.The Mayo conservative hip: complication analysis and management of the first 41cases performed at a University level 1 department. BMC Musculoskelet Disord.2017 Jun 9;18(1):250. doi: 10.1186/s12891-017-1613-2.
• Boelch SP, Jordan MC, Arnholdt J, Rudert M, Luedemann M, Steinert AF. Loading with vancomycin does not decrease gentamicin elution in gentamicin premixed bone cement. J Mater Sci Mater Med. 2017 Jul;28(7):104. doi:10.1007/s10856-017-5915-6. Epub 2017 May 22.
• Konrads C, Rueckl K, Barthel T, Walcher M, Rudert M, Plumhoff P. [Refixationof the biceps tendon onto the radial tuberosity using two suture anchors]. OperOrthop Traumatol. 2017 Aug;29(4):339-352. doi: 10.1007/s00064-017-0495-7. Epub2017 May 3. German. Erratum in: Oper Orthop Traumatol. 2017 May 23.
• Armbruster N, Krieg J, Weißenberger M, Scheller C, Steinert AF. RescuedChondrogenesis of Mesenchymal Stem Cells under Interleukin 1 Challenge byFoamyviral Interleukin 1 Receptor Antagonist Gene Transfer. Front Pharmacol. 2017May 9;8:255. doi: 10.3389/fphar.2017.00255. eCollection 2017.
• Kühn S, Lorenz RC, Weichenberger M, Becker M, Haesner M, O'Sullivan J,Steinert A, Steinhagen-Thiessen E, Brandhorst S, Bremer T, Gallinat J. Takingcontrol! Structural and behavioural plasticity in response to game-basedinhibition training in older adults. Neuroimage. 2017 May 17;156:199-206. doi:10.1016/j.neuroimage.2017.05.026. 
• Seefried L, Baumann J, Hemsley S, Hofmann C, Kunstmann E, Kiese B, Huang Y, Chivers S, Valentin MA, Borah B, Roubenoff R, Junker U, Jakob F. Efficacy of anti-sclerostin monoclonal antibody BPS804 in adult patients with hypophosphatasia. J Clin Invest. 2017 Jun 1;127(6):2148-2158. doi: 10.1172/JCI83731. Epub 2017 Apr 24.
• Glorieux FH, Devogelaer JP, Durigova M, Goemaere S, Hemsley S, Jakob F, Junker U, Ruckle J, Seefried L, Winkle PJ. BPS804 Anti-Sclerostin Antibody in Adults With Moderate Osteogenesis Imperfecta: Results of a Randomized Phase 2a Trial. J Bone Miner Res. 2017 Jul;32(7):1496-1504. doi: 10.1002/jbmr.3143. Epub 2017 Apr 19.
• Horas K, Fraissler L, Maier G, Jakob F, Seefried L, Konrads C, Rudert M, Walcher M. High Prevalence of Vitamin D Deficiency in Patients With Bone Marrow Edema Syndrome of the Foot and Ankle. Foot Ankle Int. 2017 Jul;38(7):760-766. doi: 10.1177/1071100717697427. Epub 2017 Mar 24.
• Seefried L, Mueller-Deubert S, Schwarz T, Lind T, Mentrup B, Kober M, Docheva D, Liedert A, Kassem M, Ignatius A, Schieker M, Claes L, Wilke W, Jakob F, Ebert R. A small scale cell culture system to analyze mechanobiology using reporter gene constructs and polyurethane dishes. Eur Cell Mater. 2010 Dec 10;20:344-55.
• Rueckl K, Konrads C, Barthel T, Rudert M, Boettner F, Plumhoff P. Arthroskopische Therapie bei spinoglenoidalem Ganglion. Z Orthop Unfall. 2017 Feb;155(1):100-103. doi: 10.1055/s-0043-100628. German.
• Baldwin JG, Wagner F, Martine LC, Holzapfel BM, Theodoropoulos C, Bas O, Savi FM, Werner C, De-Juan-Pardo EM, Hutmacher DW. Periosteum tissue engineering in an orthotopic in vivo platform. Biomaterials. 2017 Mar;121:193-204. doi: 10.1016/j.biomaterials.2016.11.016.
• Arnholdt J, Holzapfel BM, Sefrin L, Rudert M, Beckmann J, Steinert AF. [Individualized unicondylar knee replacement : Use of patient-specific implants and instruments]. Oper Orthop Traumatol. 2017 Feb;29(1):31-39. doi: 10.1007/s00064-017-0485-9. German.
• Steinert AF, Beckmann J, Holzapfel BM, Rudert M, Arnholdt J. Bicompartmental individualized knee replacement : Use of patient-specific implants and instruments (iDuo™). Oper Orthop Traumatol. 2017 Feb;29(1):51-58. doi: 10.1007/s00064-017-0484-x.
• Seefried L, Mueller-Deubert S, Schwarz T, Lind T, Mentrup B, Kober M, Docheva D, Liedert A, Kassem M, Ignatius A, Schieker M, Claes L, Wilke W, Jakob F, Ebert R. A small scale cell culture system to analyze mechanobiology using reporter gene constructs and polyurethane dishes. Eur Cell Mater. 2010 Dec 10;20:344-55.
• Simann M, Le Blanc S, Schneider V, Zehe V, Lüdemann M, Schütze N, Jakob F, Schilling T. Canonical FGFs Prevent Osteogenic Lineage Commitment and Differentiation of Human Bone Marrow Stromal Cells Via ERK1/2 Signaling. J Cell Biochem. 2017 Feb;118(2):263-275. doi: 10.1002/jcb.25631.
• Braun AC, Gutmann M, Ebert R, Jakob F, Gieseler H, Lühmann T, Meinel L. Matrix Metalloproteinase Responsive Delivery of Myostatin Inhibitors. Pharm Res. 2017 Jan;34(1):58-72. doi: 10.1007/s11095-016-2038-6. PubMed PMID: 27628627.
• Mentrup B, Girschick H, Jakob F, Hofmann C. A homozygous intronic branch-point deletion in the ALPL gene causes infantile hypophosphatasia. Bone. 2017 Jan;94:75-83. doi: 10.1016/j.bone.2016.10.022.

• Konrads C, Rückl K, El Tabbakh M, Rudert M, Kircher S, Plumhoff P. Therapy-resistant septic olecranon bursitis due to Mycobacterium gordonae. SICOT J. 2016;2:41.
• Wittmann K, Sieber C, von Stengel S, Kohl M, Freiberger E, Jakob F, Lell M, Engelke K, Kemmler W. Impact of whole body electromyostimulation on cardiometabolic risk factors in older women with sarcopenic obesity: the randomized controlled FORMOsA-sarcopenic obesity study. Clin Interv Aging. 2016 Nov 18;11:1697-1706.
• Hoberg M, Holzapfel BM, Steinert AF, Kratzer F, Walcher M, Rudert M. [Treatment of acetabular bone defects in revision hip arthroplasty using the Revisio-System]. Orthopade. 2017 Feb;46(2):126-132. doi: 10.1007/s00132-016-3375-1. German.
• Aeby M, Wyss T, Mentrup B, Kunstmann E, Jakob F, Aeberli D. Low-energy trauma-induced intercondylar femoral fracture. Clin Cases Miner Bone Metab. 2016 May-Aug;13(2):151-153.
• Konrads C, Reppenhagen S, Belder D, Goebel S, Rudert M, Barthel T. Long-term outcome of anterior cruciate ligament tear without reconstruction: a longitudinal prospective study. Int Orthop. 2016 Oct 3.
• Dotterweich J, Schlegelmilch K, Keller A, Geyer B, Schneider D, Zeck S, Tower RJ, Ebert R, Jakob F, Schütze N. Contact of myeloma cells induces a characteristic transcriptome signature in skeletal precursor cells -Implications for myeloma bone disease. Bone. 2016 Aug 9;93:155-166. doi: 10.1016/j.bone.2016.08.006.
• Holzapfel BM, Wagner F, Martine LC, Reppenhagen S, Rudert M, Schuetz M, Denham J, Schantz JT, Hutmacher DW. Tissue engineering and regenerative medicine in musculoskeletal oncology. Cancer Metastasis Rev. 2016 Sep;35(3):475-87. doi: 10.1007/s10555-016-9635-z.
• Maier GS, Kolbow K, Lazovic D, Horas K, Roth KE, Seeger JB, Maus U. Risk factors for pelvic insufficiency fractures and outcome after conservative therapy. Arch Gerontol Geriatr. 2016 Nov-Dec;67:80-5. doi: 10.1016/j.archger.2016.06.020. Epub 2016 Jul 15.
• Maier GS, Maus U, Lazovic D, Horas K, Roth KE, Kurth AA. Is there an association between low serum 25-OH-D levels and the length of hospital stay in orthopaedic patients after arthroplasty? J Orthop Traumatol. 2016 Dec;17(4):297-302.
• Horas K, Schnettler R, Maier G, Horas U. A novel intramedullary callus distraction system for the treatment of femoral bone defects. Strategies Trauma Limb Reconstr. 2016 Aug;11(2):113-21. doi: 10.1007/s11751-016-0255-5. Epub 2016 May 24.
• Kamawal Y, Steinert AF, Holzapfel BM, Rudert M, Barthel T. Case report - calcification of the medial collateral ligament of the knee with simultaneous calcifying tendinitis of the rotator cuff. BMC Musculoskelet Disord. 2016 Jul 13;17(1):283. doi: 10.1186/s12891-016-1147-z.
• Wagner F, Holzapfel BM, Thibaudeau L, Straub M, Ling MT, Grifka J, Loessner D, Lévesque JP, Hutmacher DW. A Validated Preclinical Animal Model for Primary Bone Tumor Research. J Bone Joint Surg Am. 2016 Jun 1;98(11):916-25. doi: 10.2106/JBJS.15.00920.
• Poh PS, Hutmacher DW, Holzapfel BM, Solanki AK, Woodruff MA. Data for accelerated degradation of calcium phosphate surface-coated polycaprolactone and polycaprolactone/bioactive glass composite scaffolds. Data Brief. 2016 Jan 22;7:923-6. doi: 10.1016/j.dib.2016.01.023. eCollection 2016 Jun.
• Steinert AF, Holzapfel BM, Sefrin L, Arnholdt J, Hoberg M, Rudert M. [Total knee arthroplasty : Patient-specific instruments and implants]. Orthopade. 2016 Apr;45(4):331-40. doi: 10.1007/s00132-016-3246-9. German.
• Holzapfel NP, Holzapfel BM, Theodoropoulos C, Kaemmerer E, Rausch T, Feldthusen J, Champ S, Clements JA, Hutmacher DW, Loessner D. Lycopene's Effects on Cancer Cell Functions within Monolayer and Spheroid Cultures. Nutr Cancer. 2016 Feb-Mar;68(2):350-63. doi: 10.1080/01635581.2016.1150498. Epub 2016 Mar 25.
• Kemmler W, Teschler M, Weissenfels A, Bebenek M, von Stengel S, Kohl M, Freiberger E, Goisser S, Jakob F, Sieber C, Engelke K. Whole-body electromyostimulation to fight sarcopenic obesity in community-dwelling older women at risk. Resultsof the randomized controlled FORMOsA-sarcopenic obesity study. Osteoporos Int. 2016 Nov;27(11):3261-3270.
• Konrads C, Reppenhagen S, Plumhoff P, Rudert M, Steinert A, Barthel T. Nail-patella-syndrome in a young patient followed up over 10 years: relevance of the sagittal trochlear septum for patellofemoral pathology. SICOT J. 2016;2:26. doi: 10.1051/sicotj/2016017. Epub 2016 May 31.
• Brunner U, Rückl K, Konrads C, Rudert M, Plumhoff P. Gorham-Stout syndrome of the shoulder. SICOT J. 2016;2:25. doi: 10.1051/sicotj/2016015. Epub 2016 May 16.
• Wesselsky V, Kitz C, Jakob F, Eulert J, Raab P. Description and evaluation of operative deformity correction in calcium-deficiency rickets in Kaduna, northern Nigeria. Int Orthop. 2016 Apr;40(4):653-8. doi: 10.1007/s00264-015-2911-7. Epub 2015 Jul 30.
• Dotterweich J, Tower RJ, Brandl A, Müller M, Hofbauer LC, Beilhack A, Ebert R, Glüer CC, Tiwari S, Schütze N, Jakob F. The KISS1 Receptor as an In Vivo Microenvironment Imaging Biomarker of Multiple Myeloma Bone Disease. PLoS One. 2016 May 9;11(5):e0155087. doi: 10.1371/journal.pone.0155087. eCollection 2016.
• Reboredo JW, Weigel T, Steinert A, Rackwitz L, Rudert M, Walles H. Investigation of Migration and Differentiation of Human Mesenchymal Stem Cells on Five-Layered Collagenous Electrospun Scaffold Mimicking Native Cartilage Structure. Adv Healthc Mater. 2016 Sep;5(17):2191-8. doi: 10.1002/adhm.201600134. Epub 2016 May 17.
• Wilken F, Banke IJ, Hauschild M, Winkler S, Schott K, Rudert M, Eisenhart-Rothe RV. [Endoprosthetic tumor replacement : Reconstruction of the extensor mechanism and complications]. Orthopade. 2016 May;45(5):439-45. doi: 10.1007/s00132-016-3255-8. German.
• Rudert M, Horas K, Hoberg M, Steinert A, Holzapfel DE, Hübner S, Holzapfel BM. The Wuerzburg procedure: the tensor fasciae latae perforator is a reliable anatomical landmark to clearly identify the Hueter interval when using the minimally-invasive direct anterior approach to the hip joint. BMC Musculoskelet Disord. 2016 Feb 3;17(1):57. doi: 10.1186/s12891-016-0908-z.
• Diener S, Bayer S, Sabrautzki S, Wieland T, Mentrup B, Przemeck GK, Rathkolb B, Graf E, Hans W, Fuchs H, Horsch M, Schwarzmayr T, Wolf E, Klopocki E, Jakob F, Strom TM, Hrabě de Angelis M, Lorenz-Depiereux B. Exome sequencing identifies a nonsense mutation in Fam46a associated with bone abnormalities in a new mouse model for skeletal dysplasia. Mamm Genome. 2016 Apr;27(3-4):111-21. doi: 10.1007/s00335-016-9619-x. Epub 2016 Jan 23.

• Wesselsky V, Kitz C, Jakob F, Eulert J, Raab P. Description and evaluation of operative deformity correction in calcium-deficiency rickets in Kaduna, northern Nigeria. Int Orthop. 2016 Apr;40(4):653-8. doi: 10.1007/s00264-015-2911-7. Epub 2015 Jul 30.
• Boelch SP, Barthel T, Goebel S, Rudert M, Plumhoff P. Calcinosis Universalis of the Elbow: A Rare Case with Classical Presentation. Case Rep Orthop. 2015;2015:505420. doi: 10.1155/2015/505420. Epub 2015 Oct 22.
• Reppenhagen S, Gilbert F, Konrads C, Göbel S, Steinert A, Hoberg M, Löffler C, Rudert M, Barthel T. [Gracilis tendon augmented reconstruction of the medial patellofemoral ligament with soft tissue fixation at the patellar insertion site]. Oper Orthop Traumatol. 2015 Dec;27(6):484-94. doi: 10.1007/s00064-015-0428-2. Epub 2015 Nov 16. German.
• Maier GS, Horas K, Kurth AA, Lazovic D, Seeger JB, Maus U. Prevalence of Vitamin D Deficiency in Patients with Bone Metastases and Multiple Myeloma. Anticancer Res. 2015 Nov;35(11):6281-5.
• Le Blanc S, Simann M, Jakob F, Schütze N, Schilling T. Fibroblast growth factors 1 and 2 inhibit adipogenesis of human bone marrow stromal cells in 3D collagen gels. Exp Cell Res. 2015 Nov 1;338(2):136-48. doi: 10.1016/j.yexcr.2015.09.009. Epub 2015 Sep 15.
• Konrads C, Reppenhagen S, Hoberg M, Rudert M, Barthel T. [Sliding osteotomy of the tibial tuberosity in patellofemoral instability]. Oper Orthop Traumatol. 2015 Dec;27(6):464-73. doi: 10.1007/s00064-015-0421-9. Epub 2015 Sep 23. German.
• Holzapfel BM, Hutmacher DW, Nowlan B, Barbier V, Thibaudeau L, Theodoropoulos C, Hooper JD, Loessner D, Clements JA, Russell PJ, Pettit AR, Winkler IG, Levesque JP. Tissue engineered humanized bone supports human hematopoiesis in vivo. Biomaterials. 2015 Aug;61:103-14. doi: 10.1016/j.biomaterials.2015.04.057. Epub 2015 May 19.
• Chhaya MP, Melchels FP, Holzapfel BM, Baldwin JG, Hutmacher DW. Sustained regeneration of high-volume adipose tissue for breast reconstruction using computer aided design and biomanufacturing. Biomaterials. 2015 Jun;52:551-60. doi: 10.1016/j.biomaterials.2015.01.025. Epub 2015 Mar 18.
• Hoberg M, Konrads C, Huber S, Reppenhagen S, Walcher M, Steinert A, Barthel T, Rudert M. Outcome of a modular head-neck adapter system in revision hip arthroplasty. Arch Orthop Trauma Surg. 2015 Oct;135(10):1469-74. doi: 10.1007/s00402-015-2281-z. Epub 2015 Jul 18.
• Ebert R, Benisch P, Krug M, Zeck S, Meißner-Weigl J, Steinert A, Rauner M, Hofbauer L, Jakob F. Acute phase serum amyloid A induces proinflammatory cytokines and mineralization via toll-like receptor 4 in mesenchymal stem cells. Stem Cell Res. 2015 Jul;15(1):231-9. doi: 10.1016/j.scr.2015.06.008. Epub 2015 Jun 23.
• Hochleitner G, Jüngst T, Brown TD, Hahn K, Moseke C, Jakob F, Dalton PD, Groll J. Additive manufacturing of scaffolds with sub-micron filaments via melt electrospinning writing. Biofabrication. 2015 Jun 12;7(3):035002. doi: 10.1088/1758-5090/7/3/035002.
• Steinert AF, Kunz M, Prager P, Göbel S, Klein-Hitpass L, Ebert R, Nöth U, Jakob F, Gohlke F. Characterization of bursa subacromialis-derived mesenchymal stem cells. Stem Cell Res Ther. 2015 Jun 3;6:114. doi: 10.1186/s13287-015-0104-3.
• Hoberg M, Konrads C, Engelien J, Oschmann D, Holder M, Walcher M, Steinert A, Rudert M. Similar outcomes between two-stage revisions for infection and aseptic hip revisions. Int Orthop. 2016 Mar;40(3):459-464. Epub 2015 Jul 2.
• Graser S, Mentrup B, Schneider D, Klein-Hitpass L, Jakob F, Hofmann C. Overexpression of tissue-nonspecific alkaline phosphatase increases the expression of neurogenic differentiation markers in the human SH-SY5Y neuroblastoma cell line. Bone. 2015 Oct;79:150-61. doi: 10.1016/j.bone.2015.05.033. Epub 2015 May 29.
• Steinert AF, Kunz M, Prager P, Göbel S, Klein-Hitpass L, Ebert R, Nöth U, Jakob F, Gohlke F. Characterization of bursa subacromialis-derived mesenchymal stem cells. Stem Cell Res Ther. 2015 Jun 3;6:114. doi: 10.1186/s13287-015-0104-3.
• Holzapfel BM, Hutmacher DW, Nowlan B, Barbier V, Thibaudeau L, Theodoropoulos C, Hooper JD, Loessner D, Clements JA, Russell PJ, Pettit AR, Winkler IG, Levesque JP. Tissue engineered humanized bone supports human hematopoiesis in vivo. Biomaterials. 2015 Aug;61:103-14. doi: 10.1016/j.biomaterials.2015.04.057. Epub 2015 May 19.
• Tang KD, Holzapfel BM, Liu J, Lee TK, Ma S, Jovanovic L, An J, Russell PJ, Clements JA, Hutmacher DW, Ling MT. Tie-2 regulates the stemness and metastatic properties of prostate cancer cells. Oncotarget. 2016 Jan 19;7(3):2572-84. doi: 10.18632/oncotarget.3950.
• Simann M, Schneider V, Le Blanc S, Dotterweich J, Zehe V, Krug M, Jakob F, Schilling T, Schütze N. Heparin affects human bone marrow stromal cell fate: Promoting osteogenic and reducing adipogenic differentiation and conversion. Bone. 2015 Sep;78:102-13. doi: 10.1016/j.bone.2015.04.039. Epub 2015 May 7.
• Chhaya MP, Melchels FP, Holzapfel BM, Baldwin JG, Hutmacher DW. Sustained regeneration of high-volume adipose tissue for breast reconstruction using computer aided design and biomanufacturing. Biomaterials. 2015 Jun;52:551-60. doi: 10.1016/j.biomaterials.2015.01.025. Epub 2015 Mar 18.
• Reichert JC, Volkmann MR, Koppmair M, Rackwitz L, Lüdemann M, Rudert M, Nöth U. Comparative retrospective study of the direct anterior and transgluteal approaches for primary total hip arthroplasty. Int Orthop. 2015 Dec;39(12):2309-13. doi: 10.1007/s00264-015-2732-8. Epub 2015 Mar 21.
• Rudert M, Holzapfel BM, von Rottkay E, Holzapfel DE, Noeth U. Impaction bone grafting for the reconstruction of large bone defects in revision knee arthroplasty. Oper Orthop Traumatol. 2015 Feb;27(1):35-46. doi: 10.1007/s00064-014-0330-3. Epub 2015 Feb 4.
• Yorgan TA, Peters S, Jeschke A, Benisch P, Jakob F, Amling M, Schinke T. The Anti-Osteoanabolic Function of Sclerostin Is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5. J Bone Miner Res. 2015 Jul;30(7):1175-83. doi: 10.1002/jbmr.2461. Epub 2015 Jun 8.
• Sieker JT, Kunz M, Weißenberger M, Gilbert F, Frey S, Rudert M, Steinert AF. Direct bone morphogenetic protein 2 and Indian hedgehog gene transfer for articular cartilage repair using bone marrow coagulates. Osteoarthritis Cartilage. 2015 Mar;23(3):433-42. doi: 10.1016/j.joca.2014.11.008. Epub 2014 Nov 13.

• Ebert R, Meissner-Weigl J, Zeck S, Määttä J, Auriola S, Coimbra de Sousa S, Mentrup B, Graser S, Rachner TD, Hofbauer LC, Jakob F. Probenecid as a sensitizer of bisphosphonate-mediated effects in breast cancer cells. Mol Cancer. 2014 Dec 11;13(1):265.
• Konrads C, Brieske S, Holder M, Walcher M, Rudert M, Hoberg M. Outcome of isolated polyethylene tibial insert exchange after primary cemented total knee arthroplasty. Int Orthop. 2015 Jun;39(6):1093-7. doi: 10.1007/s00264-014-2595-4. Epub 2014 Nov 23.
• Wehrle E, Liedert A, Heilmann A, Wehner T, Bindl R, Fischer L, Haffner-Luntzer M, Jakob F, Schinke T, Amling M, Ignatius A. The impact of low-magnitude high-frequency vibration on fracture healing is profoundly influenced by the oestrogen status in mice. Dis Model Mech. 2015 Jan;8(1):93-104. doi: 10.1242/dmm.018622. Epub 2014 Nov 7.
• Konrads C, Wente MN, Plitz W, Rudert M, Hoberg M. [Damage to implants due to high-frequency electrocautery : Analysis of four fractured hip endoprostheses shafts]. Orthopade. 2014 Dec;43(12):1106-11. doi: 10.1007/s00132-014-3023-6.
• Holzapfel BM, Nöth U, Rudert M. A simple technique to seal the medullary canal in cemented revision arthroplasty. Eur J Orthop Surg Traumatol. 2015 Apr;25(3):601-2. doi: 10.1007/s00590-014-1530-0. Epub 2014 Sep 9.
• Thiele S, Göbel A, Rachner TD, Fuessel S, Froehner M, Muders MH, Baretton GB, Bernhardt R, Jakob F, Glüer CC, Bornhäuser M, Rauner M, Hofbauer LC. WNT5A has anti-prostate cancer effects in vitro and reduces tumor growth in the skeleton in vivo. J Bone Miner Res. 2015 Mar;30(3):471-80. doi: 10.1002/jbmr.2362.
• Schlegelmilch K, Keller A, Zehe V, Hondke S, Schilling T, Jakob F, Klein-Hitpass L, Schütze N. WISP 1 is an important survival factor in human mesenchymal stromal cells. Gene. 2014 Nov 10;551(2):243-54. doi: 10.1016/j.gene.2014.09.002. Epub 2014 Sep 6. 
• Liedert A, Röntgen V, Schinke T, Benisch P, Ebert R, Jakob F, Klein-Hitpass L, Lennerz JK, Amling M, Ignatius A. Osteoblast-Specific Krm2 Overexpression and Lrp5 Deficiency Have Different Effects on Fracture Healing in Mice. PLoS One. 2014 Jul 25;9(7):e103250. doi: 10.1371/journal.pone.0103250.
• Nekova TS, Dotterweich J, Schütze N, Einsele H, Stuhler G. Small Molecule Enhancers of Rapamycin induce apoptosis in Myeloma cells via GSK3A/B preferentially within a protective bone marrow microenvironment. Br J Haematol. 2014 Jun 11.
• Sieker JT, Rudert M, Steinert AF. Symptomatic loosening of a total knee arthroplasty caused by a tibial chondrosarcoma - a case report. Springerplus. 2014 Jun 24;3:308. doi: 10.1186/2193-1801-3-308. eCollection 2014.
• Dotterweich J, Ebert R, Kraus S, Tower RJ, Jakob F, Schütze N. Mesenchymal stem cell contact promotes CCN1 splicing and transcription in myeloma cells. Cell Commun Signal. 2014 Jun 25;12:36. doi: 10.1186/1478-811X-12-36.
• Wobus M, List C, Dittrich T, Dhawan A, Duryagina R, Arabanian LS, Kast K, Wimberger P, Stiehler M, Hofbauer LC, Jakob F, Ehninger G, Anastassiadis K, Bornhäuser M. Breast carcinoma cells modulate the chemoattractive activity of human bone marrow-derived mesenchymal stromal cells by interfering with CXCL12. Int J Cancer. 2015 Jan 1;136(1):44-54. doi: 10.1002/ijc.28960. Epub 2014 May 20
• Wehrle E, Wehner T, Heilmann A, Bindl R, Claes L, Jakob F, Amling M, Ignatius A. Distinct frequency dependent effects of whole-body vibration on non-fractured bone and fracture healing in mice. J Orthop Res. 2014 Aug;32(8):1006-13. doi: 10.1002/jor.22629. Epub 2014 Apr 14.
• Holzapfel BM, Pilge H, Prodinger PM, Toepfer A, Mayer-Wagner S, Hutmacher DW, von Eisenhart-Rothe R, Rudert M, Gradinger R, Rechl H. Customised osteotomy guides and endoprosthetic reconstruction for periacetabular tumours. Int Orthop. 2014 Jul;38(7):1435-42.
• Rachner TD, Göbel A, Thiele S, Rauner M, Benad-Mehner P, Hadji P, Bauer T, Muders MH, Baretton GB, Jakob F, Ebert R, Bornhäuser M, Schem C, Hofbauer LC. Dickkopf-1 is regulated by the mevalonate pathway in breast cancer. Breast Cancer Res. 2014 Feb 14;16(1):R20. doi: 10.1186/bcr3616.
• Hofmann C, Girschick H, Mornet E, Schneider D, Jakob F, Mentrup B. Unexpected high intrafamilial phenotypic variability observed in hypophosphatasia. Eur J Hum Genet. 2014 Oct;22(10):1160-4. doi: 10.1038/ejhg.2014.10. Epub 2014 Feb 26.

• Nedopil AJ, Howell SM, Rudert M, Roth J, Hull ML. How frequent is rotational mismatch within 0°±10° in kinematically aligned total knee arthroplasty? rthopedics. 2013 Dec;36(12):e1515-20.
• Lapa C, Genest F, Buck AK, Herrmann K, Kenn W, Rudert M, Jakob F, Seefried L. Diagnostic findings and treatment in a 51-year-old woman with oncogenic osteomalacia. J Clin Endocrinol Metab. 2014 Feb;99(2):385-6. doi: 10.1210/jc.2013-3980. Epub 2013 Dec 11.
• Scharla S, Oertel H, Petto H, Jakob F. Frakturen, Rückenschmerzen, Lebensqualität und Compliance unter einer Teriparatid-Therapie bei Patientinnen mit postmenopausaler Osteoporose in Deutschland - Subgruppen-Analyse der prospektiven europäischen Langzeit Anwendungsbeobachtung EFOS1 (Fractures, back pain, quality of life, and compliance in German postmenopausal patients with osteoporosis treated with teriparatide Subgroup analysis of the European Forsteo® Observational Study (EFOS). Osteologie / Osteology 2013 22 3: 214-222
• Schmitz P, Gerber U, Schütze N, Jüngel E, Blaheta R, Naggi A, Torri G, Bendas G. Cyr61 is a target for heparin in reducing MV3 melanoma cell adhesion and migration via the integrin VLA-4. Thromb Haemost. 2013 Nov;110(5):1046-54. doi: 10.1160/TH13-02-0158. Epub 2013 Sep 5.
• Mornet E, Hofmann C, Bloch-Zupan A, Girschick H, Le Merrer M. Clinical utility gene card for: hypophosphatasia - update 2013. Eur J Hum Genet. 2014 Apr;22(4). doi: 10.1038/ejhg.2013.177. Epub 2013 Aug 7.
• Reichert JC, Schmalzl J, Prager P, Gilbert F, Quent VM, Steinert AF, Rudert M, Nöth U. Synergistic effect of Indian hedgehog and bone morphogenetic protein-2 gene transfer to increase the osteogenic potential of human mesenchymal stem cells. Stem Cell Res Ther. 2013;4(5):105.
• Berner A, Reichert JC, Woodruff MA, Saifzadeh S, Morris AJ, Epari DR, Nerlich M, Schuetz MA, Hutmacher DW. Autologous vs. allogenic mesenchymal progenitor cells for the reconstruction of critical sized segmental tibial bone defects in aged sheep. Acta Biomater. 2013 Aug;9(8):7874-84. doi:10.1016/j.actbio.2013.04.035. Epub 2013 Apr 27.
• Reichert JC, Gohlke J, Friis TE, Quent VM, Hutmacher DW. Mesodermal and neural crest derived ovine tibial and mandibular osteoblasts display distinct molecular differences. Gene. 2013 Aug 1;525(1):99-106. doi: 10.1016/j.gene.2013.04.026. Epub 2013 Apr 28.
• Ljunggren Ö, Barrett A, Stoykov I, Langdahl BL, Lems WF, Walsh JB, Fahrleitner-Pammer A, Rajzbaum G, Jakob F, Karras D, Marin F. Effective osteoporosis treatment with teriparatide is associated with enhanced quality of life in postmenopausal women with osteoporosis: the European Forsteo Observational Study. BMC Musculoskelet Disord. 2013 Aug 22;14:251. doi: 10.1186/1471-2474-14-251.
• Pilge H, Holzapfel BM, Lampe R, Pilge S, Prodinger PM. A novel technique to treat Grisel's syndrome: results of a simplified, therapeutical algorithm. Int Orthop. 2013 Jul;37(7):1307-13. doi: 10.1007/s00264-013-1895-4. Epub 2013 May 9.
• Prodinger PM, Pilge H, Banke IJ, Bürklein D, Gradinger R, Miethke T, Holzapfel BM. Acute osteomyelitis of the humerus mimicking malignancy: Streptococcus pneumoniae as exceptional pathogen in an immunocompetent adult. BMC Infect Dis. 2013 Jun 5;13:266. doi: 10.1186/1471-2334-13-266.
• Prodinger PM, Rechl H, Keller M, Pilge H, Salzmann M, von Eisenhart-Rothe R, Holzapfel BM. Surgical resection and radiation therapy of desmoid tumours of the extremities: results of a supra-regional tumour centre. Int Orthop. 2013 Oct;37(10):1987-93. doi: 10.1007/s00264-013-1942-1. Epub 2013 Jun 22.
• Nedopil A, Raab P, Rudert M. Desmoplastic fibroma: a case report with three years of clinical and radiographic observation and review of the literature. Open Orthop J. 2013;8:40-6. doi: 10.2174/1874325001307010040. Epub 2013 Feb 13.
• Kohler J, Popov C, Klotz B, Alberton P, Prall WC, Haasters F, Müller-Deubert S, Ebert R, Klein-Hitpass L, Jakob F, Schieker M, Docheva D. Uncovering the cellular and molecular changes in tendon stem/progenitor cells attributed to tendon aging and degeneration. Aging Cell. 2013 Dec;12(6):988-99. doi: 10.1111/acel.12124. Epub 2013 Jul 22.
• Mittag F, Leichtle C, Kieckbusch I, Wolburg H, Rudert M, Kluba T, Leichtle U. Cytotoxic effect and tissue penetration of phenol for adjuvant treatment of giant cell tumours. Oncol Lett. 2013 May;5(5):1595-1598. Epub 2013 Mar 11.
• Scherzed A, Hackenberg S, Froelich K, Rak K, Technau A, Radeloff A, Nöth U, Koehler C, Hagen R, Kleinsasser N. Effects of salinomycin on human bone marrow-derived mesenchymal stem cells in vitro. Toxicol Lett. 2013 Apr 26;218(3):207-14. doi: 10.1016/j.toxlet.2013.02.001. Epub 2013 Feb 12.
• Wimmer MD, Randau TM, Deml MC, Ascherl R, Nöth U, Forst R, Gravius N, Wirtz D, Gravius S. Impaction grafting in the femur in cementless modular revision total hip arthroplasty: a descriptive outcome analysis of 243 cases with the MRP-TITAN revision implant. BMC Musculoskelet Disord. 2013 Jan 11;14:19. doi: 10.1186/1471-2474-14-19.
• Weber C, Armbruster N, Scheller C, Kreppel F, Kochanek S, Rethwilm A, Steinert AF. Foamy virus-adenovirus hybrid vectors for gene therapy of the arthritides. J Gene Med. 2013 Mar;15(3-4):155-67. doi: 10.1002/jgm.2705.
• Goebel S, Steinert A, Vierheilig C, Faller H. Correlation between depressive symptoms and perioperative pain: a prospective cohort study of patients undergoing orthopedic surgeries. Clin J Pain. 2013 May;29(5):392-9. doi: 10.1097/AJP.0b013e318262e2c8.
• Schmitz P, Gerber U, Jüngel E, Schütze N, Blaheta R, Bendas G. Cyr61/CCN1 affects the integrin-mediated migration of prostate cancer cells (PC-3) in vitro. Int J Clin Pharmacol Ther. 2013 Jan;51(1):47-50.
• Schmidt K, Jakubietz M, Harenberg P, Holzapfel BM, Rudert M, Meffert R, Jakubietz R. [The distally based adipofascial sural artery flap for the reconstruction of distal lower extremity defects]. Oper Orthop Traumatol. 2013 Apr;25(2):162-9.
• Al-Ibraheem A, Buck AK, Benz MR, Rudert M, Beer AJ, Mansour A, Pomykala KL, Haller B, Juenger H, Scheidhauer K, Schwaiger M, Herrmann K. (18) F-Fluorodeoxyglucose positron emission tomography/computed tomography for the detection of recurrent bone and soft tissue sarcoma. Cancer. 2013 Mar 15;119(6):1227-34.
• Nedopil A, Raab P, Rudert M. Desmoplastic fibroma: a case report with three years of clinical and radiographic observation and review of the literature. Open Orthop J. 2013;8:40-6. doi: 10.2174/1874325001307010040. Epub 2013 Feb 13.
• Audran M, Jakob FJ, Palacios S, Brandi ML, Bröll H, Hamdy NA, McCloskey EV. A large prospective European cohort study of patients treated with strontium ranelate and followed up over 3 years. Rheumatol Int. 2013 Sep;33(9):2231-9. doi: 10.1007/s00296-012-2594-y. Epub 2013 Mar 2.
• Hofmann C, Liese J, Schwarz T, Kunzmann S, Wirbelauer J, Nowak J, Hamann J, Girschick H, Graser S, Dietz K, Zeck S, Jakob F, Mentrup B. Compound heterozygosity of two functional null mutations in the ALPL gene associated with deleterious neurological outcome in an infant with hypophosphatasia. Bone. 2013 Jul;55(1):150-7. doi: 10.1016/j.bone.2013.02.017. Epub 2013 Feb 27.
• Goebel S, Steinert A, Vierheilig C, Faller H. Correlation Between Depressive Symptoms and Perioperative Pain: A Prospective Cohort Study of Patients Undergoing Orthopedic Surgeries. Clin J Pain. 2013 Jan 16.
• Wimmer MD, Randau TM, Deml MC, Ascherl R, Nöth U, Forst R, Gravius N, Wirtz D, Gravius S. Impaction grafting in the femur in cementless modular revision total hip arthroplasty: a descriptive outcome analysis of 243 cases with the MRP-TITAN revision implant. BMC Musculoskelet Disord. 2013 Jan 11;14:19.

• Al-Ibraheem A, Buck AK, Benz MR, Rudert M, Beer AJ, Mansour A, Pomykala KL, Haller B, Juenger H, Scheidhauer K, Schwaiger M, Herrmann K. (18) F-fluorodeoxyglucose positron emission tomography/computed tomography for the detection of recurrent bone and soft tissue sarcoma. Cancer. 2013 Mar 15;119(6):1227-34. doi: 10.1002/cncr.27866. Epub 2012 Dec 11.
• Frey SP, Doht S, Eden L, Dannigkeit S, Schuetze N, Meffert RH, Jansen H. Cysteine-rich matricellular protein improves callus regenerate in a rabbit trauma model. Int Orthop. 2012 Nov;36(11):2387-93. doi: 10.1007/s00264-012-1659-6. Epub 2012 Sep 23.
• Laug R, Fehrholz M, Schütze N, Kramer BW, Krump-Konvalinkova V, Speer CP, Kunzmann S. IFN-γ and TNF-α Synergize to Inhibit CTGF Expression in Human Lung Endothelial Cells. PLoS One. 012;7(9):e45430. doi: 10.1371/journal.pone.0045430. Epub 2012 Sep 20.
• Benisch P, Schilling T, Klein-Hitpass L, Frey SP, Seefried L, Raaijmakers N, Krug M, Regensburger M, Zeck S, Schinke T, Amling M, Ebert R, Jakob F. The transcriptional profile of mesenchymal stem cell populations in primary osteoporosis is distinct and shows overexpression of osteogenic inhibitors. PLoS One. 2012;7(9):e45142. doi: 10.1371/journal.pone.0045142. Epub 2012 Sep 24.
• Rackwitz L, Schneider U, Andereya S, Siebenlist S, Reichert JC, Fensky F, Arnholdt J, Löer I, Grossstück R, Zinser W, Barthel T, Rudert M, Nöth U. [Reconstruction of osteochondral defects with a collagen I hydrogel. Results of a prospective multicenter study]. Orthopade. 2012 Apr;41(4):268-79. German. Erratum in: Orthopade. 2012 May;41(5):412. Arnhold, J [corrected to Arnholdt, J].
• Holzapfel BM, Greimel F, Prodinger PM, Pilge H, Nöth U, Gollwitzer H, Rudert M. Total hip replacement in developmental dysplasia using an oval-shaped cementless press-fit cup. Int Orthop. 2012 Jul;36(7):1355-61. Epub 2012 Mar 1.
• Walsh JB, Lems WF, Karras D, Langdahl BL, Ljunggren O, Fahrleitner-Pammer A, Barrett A, Rajzbaum G, Jakob F, Marin F. Effectiveness of Teriparatide in Women Over 75 Years of Age with Severe Osteoporosis: 36-Month Results from the European Forsteo Observational Study EFOS). Calcif Tissue Int. 2012 May;90(5):373-83.
• Jakubietz RG, Schmidt K, Holzapfel BM, Meffert RH, Rudert M, Jakubietz MG. [Soft tissue reconstruction of the distal lower extremity using the 180-degree perforator-based propeller flap]. Oper Orthop Traumatol. 2012 Feb;24(1):43-9.
• Steinert AF, Weissenberger M, Kunz M, Gilbert F, Ghivizzani SC, Goebel S, Jakob F, Noth U, Rudert M Indian hedgehog gene transfer is a chondrogenic inducer of human mesenchymal stem cells. Arthritis Research & Therapy 2012, 14:R168 (20 July 2012)
• Goebel S, Steinert AF, Schillinger J, Eulert J, Broscheit J, Rudert M, Nöth U. Reduced postoperative pain in total hip arthroplasty after minimal-invasive anterior approach. Int Orthop. 2012 Mar;36(3):491-8. Epub 2011 May 25.
• Morbach H, Schneider P, Schwarz T, Hofmann C, Raab P, Neubauer H, Düren C, Beer M, Girschick HJ. Comparison of magnetic resonance imaging and 99mTechnetium-labelled methylene diphosphonate bone scintigraphy in the initial assessment of chronic non-bacterial osteomyelitis of childhood and adolescents. Clin Exp Rheumatol. 2012 Jul-Aug;30(4):578-82.
• Karras D, Stoykov I, Lems WF, Langdahl BL, Ljunggren Ö, Barrett A, Walsh JB, Fahrleitner-Pammer A, Rajzbaum G, Jakob F, Marin F. Effectiveness of teriparatide in postmenopausal women with osteoporosis and glucocorticoid use: 3-year results from the EFOS study. J Rheumatol. 2012 Mar;39(3):600-9. Epub 2012 Jan 15.
• Klotz B, Mentrup B, Regensburger M, Zeck S, Schneidereit J, Schupp N, Linden C, Merz C, Ebert R, Jakob F. 1,25-dihydroxyvitamin D3 treatment delays cellular aging in human mesenchymal stem cells while maintaining their multipotent capacity. PLoS One. 2012;7(1):e29959. Epub 2012 Jan 5.
• Ebert R, Zeck S, Meissner-Weigl J, Klotz B, Rachner TD, Benad P, Klein-Hitpass L, Rudert M, Hofbauer LC, Jakob F. Krüppel-like factors KLF2 and 6 and Ki-67 are direct targets of zoledronic acid in MCF-7 cells. Bone. 2012 Mar;50(3):723-32. Epub 2011 Dec 7.
• Jakob F, Oertel H, Langdahl B, Ljunggren O, Barrett A, Karras D, Walsh JB, Fahrleitner-Pammer A, Rajzbaum G, Barker C, Lems WF, Marin F. Effects of teriparatide in postmenopausal women with osteoporosis pre-treated with bisphosphonates: 36-month results from the European Forsteo Observational Study. Eur J Endocrinol. 2012 Jan;166(1):87-97. Epub 2011 Nov 2.

• Schneider U, Rackwitz L, Andereya S, Siebenlist S, Fensky F, Reichert J, Löer I, Barthel T, Rudert M, Nöth U. A prospective multicenter study on the outcome of type I collagen hydrogel-based autologous chondrocyte implantation (CaReS) for the repair of articular cartilage defects in the knee. Am J Sports Med. 2011 Dec;39(12):2558-65.
• Daentzer D, Rudert M, Wirth CJ, Stukenborg-Colsman C. Reconstruction of the patella with an autogenous iliac graft: clinical and radiologic results in thirteen patients. Int Orthop. 2012 Mar;36(3):545-52. Epub 2011 May 31.
• Reppenhagen S, Reichert JC, Rackwitz L, Rudert M, Raab P, Daculsi G, Nöth U. Biphasic bone substitute and fibrin sealant for treatment of benign bone tumours and tumour-like lesions. Int Orthop. 2012 Jan;36(1):139-48. Epub 2011 May 28.
• Steinert AF, Reppenhagen S, Baumann B, Rudert M, Nöth U. Total knee arthroplasty in a patient with erdheim-chester disease with massive joint destruction: a case report. J Bone Joint Surg Am. 2011 Apr;93(7):e29.
• Goebel S, Steinert A, Rucker A, Rudert M, Barthel T. [Minimally invasive retrograde drilling of osteochondral lesions of the femur using an arthroscopic drill guide]. Oper Orthop Traumatol. 2011 Apr;23(2):111-20. doi: 10.1007/s00064-011-0014-1. German.
• Limbert C, Päth G, Ebert R, Rothhammer V, Kassem M, Jakob F, Seufert J. PDX1- and NGN3- mediated in vitro reprogramming of human bone marrow-derived mesenchymal stromal cells into pancreatic endocrine lineages. Cytotherapy. 2011 Aug;13(7):802-13. Epub 2011 Apr 21.
• Mentrup B, Marschall C, Barvencik F, Amling M, Plendl H, Jakob F, Beck C. Functional characterization of a novel mutation localized in the start codon of the tissue-nonspecific alkaline phosphatase gene. Bone. 2011 Jun 1;48(6):1401-8. Epub 2011 Mar 16.
• Kuehnen P, Laubner K, Raile K, Schöfl C, Jakob F, Pilz I, Päth G, Seufert J. Protein Phosphatase 1 (PP-1) dependent inhibition of insulin secretion by leptin in INS-1 pancreatic beta-cells and human pancreatic islets. Endocrinology 2011, May;152(5):1800-8. Epub 2011 Mar 22.
• Reichert JC, Quent VM, Nöth U, Hutmacher DW. Ovine cortical osteoblasts outperform bone marrow cells in an ectopic bone assay. J Tissue Eng Regen Med. 2011 Nov;5(10):831-44. doi: 10.1002/term.392. Epub 2011 Feb 10.
• Thiele S, Rauner M, Goettsch C, Rachner TD, Benad P, Fuessel S, Erdmann K, Hamann C, Baretton GB, Wirth MP, Jakob F, Hofbauer LC. Expression profile of WNT molecules in prostate cancer and its regulation by aminobisphosphonates. J Cell Biochem. 2011 Jun;112(6):1593-600. doi: 10.1002/jcb.23070.
• Albers J, Schulze J, Gebauer M, Baranowsky A, Keller J, Beil FT, Marshall RP, Wintges K, Friedrich FW, Priemel M, Schilling AF, Rueger JM, Cornils K, Fehse B, Streichert T, Sauter G, Jakob F, Insogna KL, Pober B, Knobeloch KP, Francke U, Amling M, Schinke T. Control of Bone Formation by the Serpentine Receptor Frizzled-9. J Cell Biol. 2011 Mar 21;192(6):1057-72. Epub 2011 Mar 14.
• Steinert AF, Kunz M, Prager P, Barthel T, Jakob F, Nöth U, Murray MM, Evans CH, Porter RM. Mesenchymal stem cell characteristics of human anterior cruciate ligament outgrowth cells. Tissue Eng Part A. 2011 May;17(9-10):1375-88. Epub 2011 Mar 8.

• Reichert JC, Wullschleger ME, Cipitria A, Lienau J, Cheng TK, Schütz MA, Duda GN, Nöth U, Eulert J, Hutmacher DW. Custom-made composite scaffolds for segmental defect repair in long bones. Int Orthop. 2011 Aug;35(8):1229-36. Epub 2010 Dec 7.
• Fahrleitner-Pammer A, Langdahl BL, Marin F, Jakob F, Karras D, Barrett A, Ljunggren Ö, Walsh JB, Rajzbaum G, Barker C, Lems WF. Fracture rate and back pain during and after discontinuation of teriparatide: 36-month data from the European Forsteo Observational Study (EFOS). Osteoporos Int. 2011 Oct;22(10):2709-19. Epub 2010 Nov 27.
• Seefried L, Mueller-Deubert S, Schwarz T, Lind T, Mentrup B, Kober M, Docheva D, Liedert A, Kassem M, Ignatius A, Schieker M, Claes L, Wilke W, Jakob F, Ebert R. A small scale cell culture system to analyze mechanobiology using reporter gene constructs and polyurethane dishes. European Cells and Materials 2010, 20:344-355.
• Lyritis G, Marin F, Barker C, Pfeifer M, Farrerons J, Brixen K, del Pino J, Keen R, Nickelsen TN; EUROFORS Study Group (F Jakob as an investigator). Back pain during different sequential treatment regimens of teriparatide: results from EUROFORS. Curr Med Res Opin. 2010 Aug;26(8):1799-807.
• Klug G, Kampf T, Bloemer S, Bremicker J, Ziener CH, Heymer A, Gbureck U, Rommel E, Nöth U, Schenk WA, Jakob PM, Bauer WR. Intracellular and extracellular T(1) and T(2) relaxivities of magneto-optical nanoparticles at experimental high fields. Magn Reson Med. 2010 Dec;64(6):1607-15. doi: 10.1002/mrm.22557.
• Anderson DD, Tochigi Y, Rudert MJ, Vaseenon T, Brown TD, Amendola A. Effect of implantation accuracy on ankle contact mechanics with a metallic focal resurfacing implant. J Bone Joint Surg Am. 2010 Jun;92(6):1490-500.
• Hofbauer L, Jakob F, Felsenberg D. Atypical femur fractures and bisphosphonate use (Letter to the Editor). New England Journal of Medicine 2010, accepted for publication.
• Nedopil A, Rudert M, Gradinger R, Schuster T, Bracker W (2010) Closed Wedge osteotomy in 66 patients for the treatment of moderate to severe hallux valgus. Foot and Ankle Surgery 16: 9-14
• Goebel S, Baumann B, Steinert A, Reppenhagen S, Faller H. [Elevated postoperative pain levels following orthopedic surgery. Depression as a strong predictor]. Schmerz. 2010 Feb;24(1):54-61. German.
• Hamidouche Z, Fromigué O, Nuber U, Vaudin P, Pages JC, Ebert R, Jakob F, Miraoui H, Marie PJ. Autocrine fibroblast growth factor 18 mediates dexamethasone-induced osteogenic differentiation of murine mesenchymal stem cells. J Cell Physiol. 2010 Aug;224(2):509-15.
• Warstat K, Hoberg M, Rudert M, Tsui S, Pap T, Angres B, Essl M, Smith TJ, Cruikshank WW, Klein G, Gay S, Aicher WK. Transforming growth factor beta1 and laminin-111 cooperate in the induction of interleukin-16 expression in synovial fibroblasts from patients with rheumatoid arthritis.Ann Rheum Dis. 2010 Jan;69(1):270-5.
• Haddad-Weber M, Prager P, Kunz M, Seefried L, Jakob F, Murray MM, Evans CH, Nöth U, Steinert AF. BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and anterior cruciate ligament cells. Cytotherapy. 2010 Jul;12(4):505-13.
• Liedert A, Wagner L, Seefried L, Ebert R, Jakob F, Ignatius A. Estrogen receptor and Wnt signaling interact to regulate early gene expression in response to mechanical strain in osteoblastic cells. Biochem Biophys Res Commun. 2010 Apr 9;394(3):755-9. Epub 2010 Mar 17.
• Berner A, Siebenlist S, Reichert JC, Hendrich C, Nöth U.[Reconstruction of osteochondral defects with a stem cell-based cartilage-polymer construct in a small animal model]. Z Orthop Unfall. 2010 Jan;148(1):31-8. Epub 2010 Feb 11.
• Goebel S, Baumann B, Steinert A, Reppenhagen S, Faller H. [Elevated postoperative pain levels following orthopedic surgery. Depression as a strong predictor]. Schmerz. 2010 Feb;24(1):54-61.
• Limbert C, Ebert R, Schilling T, Path G, Benisch P, Klein-Hitpass L, Seufert J, Jakob F. Functional signature of human islet-derived precursor cells compared to bone marrow-derived mesenchymal stem cells. Stem Cells Dev. 2010 May;19(5):679-91.
• Maher SA, Mauck RL, Rackwitz L, Tuan RS. A nanofibrous cell-seeded hydrogel promotes integration in a cartilage gap model. J Tissue Eng Regen Med. 2010 Jan;4(1):25-9.

• Hoberg M, Schmidt EL, Tuerk M, Stark V, Aicher WK, Rudert M (2009) Induction of endostatin expression in meniscal fibrochondrocytes by co-culture with endothelial cells. Arch Orthop Trauma Surg 129: 1137-1143.
• Reichert JC, Heymer A, Berner A, Eulert J, Nöth U. Fabrication of polycaprolactone collagen hydrogel constructs seeded with mesenchymal stem cells for bone regeneration. Biomed Mater. 2009 Dec;4(6):065001.
• Wiktorowicz T, Peters K, Armbruster N, Steinert AF, Rethwilm A. Generation of an improved foamy virus vector by dissection of cis-acting sequences. J Gen Virol. 2009 Feb;90(Pt 2):481-7.
• Steinert AF, Proffen B, Kunz M, Hendrich C, Ghivizzani SC, Nöth U, Rethwilm A, Eulert J, Evans CH. Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer. Arthritis Res Ther. 2009;11(5):R148. Epub 2009 Oct 2.
• Langdahl BL, Rajzbaum G, Jakob F, Karras D, Ljunggren O, Lems WF, Fahrleitner-Pammer A, Walsh JB, Barker C, Kutahov A, Marin F. Reduction in fracture rate and back pain and increased quality of life in postmenopausal women treated with teriparatide: 18-month data from the European Forsteo Observational Study (EFOS). Calcif Tissue Int. 2009 Dec;85(6):484-93. Epub 2009 Oct 13.
• Djouad F, Rackwitz L, Song Y, Janjanin S, Tuan RS. ERK1/2 activation induced by inflammatory cytokines compromises effective host tissue integration of engineered cartilage. Tissue Eng Part A. 2009 Oct;15(10):2825-35.
• Sekiya JK, Wickwire AC, Stehle JH, Debski RE. Hill-Sachs defects and repair using osteoarticular allograft transplantation: biomechanical analysis using a joint compression model. Am J Sports Med. 2009 Dec;37(12):2459-66. Epub 2009 Sep 2.
• Hartmann JM, Rudert MJ, Pedersen DR, Baer TE, Goreham-Voss CM, Brown TD. Compliance-dependent load allocation between sensing versus non-sensing portions of a sheet-array contact stress sensor. Iowa Orthop J. 2009;29:43-7.
• Wiktorowicz T, Peters K, Armbruster N, Steinert AF, Rethwilm A. Generation of an improved foamy virus vector by dissection of cis-acting sequences. J Gen Virol. 2009 Feb;90(Pt 2):481-7.
• Langdahl BL, Rajzbaum G, Jakob F, Karras D, Ljunggren O, Lems WF, Fahrleitner-Pammer A, Walsh JB, Barker C, Kutahov A, Marin F. Reduction in fracture rate and back pain and increased quality of life in postmenopausal women treated with teriparatide: 18-month data from the European Forsteo Observational Study (EFOS). Calcif Tissue Int. 2009 Dec;85(6):484-93. Epub 2009 Oct 13.
• Rachner TD, Singh SK, Schoppet M, Benad P, Bornhäuser M, Ellenrieder V, Ebert R, Jakob F, Hofbauer LC. Zoledronic acid induces apoptosis and changes the TRAIL/OPG ratio in breast cancer cells. Cancer Lett. 2010 Jan 1;287(1):109-16. Epub 2009 Jul 3.
• Heymer A, Bradica G, Eulert J, Nöth U. Multiphasic collagen fibre-PLA composites seeded with human mesenchymal stem cells for osteochondral defect repair: an in vitro study. J Tissue Eng Regen Med. 2009 Jul;3(5):389-97.
• Wiktorowicz T, Peters K, Armbruster N, Steinert AF, Rethwilm A. Generation of an improved foamy virus vector by dissection of cis-acting sequences. J Gen Virol. 2009 Feb;90(Pt 2):481-7.
• Ebert R, Zeck S, Krug R, Meissner-Weigl J, Schneider D, Seefried L, Eulert J, Jakob F. Pulse treatment with zoledronic acid causes sustained commitment of bone marrow derived mesenchymal stem cells for osteogenic differentiation.Bone. 2009 May;44(5):858-64. Epub 2009 Jan 23.
• Lienau J, Schmidt-Bleek K, Peters A, Haschke F, Duda GN, Perka C, Bail HJ, Schütze N, Jakob F, Schell H. Differential regulation of blood vessel formation between standard and delayed bone healing. J Orthop Res. 2009 Sep;27(9):1133-40.
• Goebel S, Lienau J, Rammoser U, Seefried L, Wintgens KF, Seufert J, Duda G, Jakob F, Ebert R. FGF23 is a putative marker for bone healing and regeneration. J Orthop Res. 2009 Sep;27(9):1141-6.

• Janjanin S, Djouad F, Shanti RM, Baksh D, Gollapudi K, Prgomet D, Rackwitz L, Joshi AS, Tuan RS. Human palatine tonsil: a new potential tissue source of multipotent mesenchymal progenitor cells. Arthritis Res Ther. 2008;10(4):R83. Epub 2008 Jul 28.
• Raab P, Ettl V, Kozuch A, Nöth U. Hypertrophy of the abductor digiti minimi muscle simulating a localised soft tissue mass. Foot Ankle Surg. 2008;14(1):43-6. Epub 2007 Dec 11.
• Steinert AF, Goebel S, Rucker A, Barthel T. Snapping elbow caused by hypertrophic synovial plica in the radiohumeral joint: a report of three cases and review of literature. Arch Orthop Trauma Surg. 2010 Mar;130(3):347-51. Epub 2008 Dec 17.
• Moore SM, Stehle JH, Rainis EJ, McMahon PJ, Debski RE. The current anatomical description of the inferior glenohumeral ligament does not correlate with its functional role in positions of external rotation.J Orthop Res. 2008 Dec;26(12):1598-604.
• Steinert AF, Palmer GD, Pilapil C, Nöth U, Evans CH, Ghivizzani SC. Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transfer. Tissue Eng Part A. 2009 May;15(5):1127-39.
• Obermayer-Pietsch BM, Marin F, McCloskey EV, Hadji P, Farrerons J, Boonen S, Audran M, Barker C, Anastasilakis AD, Fraser WD, Nickelsen T; EUROFORS Investigators (F. Jakob as an investigator). Effects of two years of daily teriparatide treatment on BMD in postmenopausal women with severe osteoporosis with and without prior antiresorptive treatment.J Bone Miner Res. 2008 Oct;23(10):1591-600.
• Goebel S, Steinert AF, Barthel T. Surgical management of a double-layered patella: a case report. Arch Orthop Trauma Surg. 2009 Aug;129(8):1071-5. Epub 2008 Aug 2.
• Boonen S, Marin F, Obermayer-Pietsch B, Simões ME, Barker C, Glass EV, Hadji P, Lyritis G, Oertel H, Nickelsen T, McCloskey EV; EUROFORS Investigators (F. Jakob as an investigator). Effects of previous antiresorptive therapy on the bone mineral density response to two years of teriparatide treatment in postmenopausal women with osteoporosis. J Clin Endocrinol Metab. 2008; 93(3):852-60. Epub 2007 Dec 26.
• Rajzbaum G, Jakob F, Karras D, Ljunggren O, Lems WF, Langdahl BL, Fahrleitner-Pammer A, Walsh JB, Gibson A, Tynan AJ, Marin F. Characterization of patients in the European Forsteo Observational Study (EFOS): postmenopausal women entering teriparatide treatment in a community setting. Curr Med Res Opin 2008; Feb;24(2):377-84.
• Kunzmann S, Seher A, Kramer BW, Schenk R, Schütze N, Jakob F, Sebald W, Speer CP. Connective tissue growth factor (CTGF) does not affect TGF-β1 induced Smad3 phosphorylation and T lymphocytes proliferation inhibition. Int Arch Allergy Imm 2008; 147(2):152-160.
• Liu H, Yang R, Tinner B, Choudry A, Schütze N, Chaqour B. Cysteine rich protein CYR61, CCN1 and connective tissue growth factor, CCN2, induce de-adhesion and anoikis of retinal pericytes. Endocrinology 2008; 149(4):1666-77.
• Ince A, Schütze N, Hendrich C, Thull R, Eulert J, Löhr JF. In vitro investigation of orthopedic titanium-coated and brushite-coated surfaces using human osteoblasts in the presence of gentamycin. J Arthroplasty. 2008 Aug;23(5):762-71. Epub 2008 Mar 4.
• Ponce M. Koelling S, Kluever A, Heinemann D, Miosge N, Wulf G, Frosch KH, Schütze N, Huefner M, Siggelkow H. Coexpression of osteogenic and adipogenic differentiation markers in selected subpopulations of primary human mesenchymal progenitor cells. J Cell Biochem 2008; 104(4):1342-55.
• Heymer A, Haddad D, Weber M, Gbureck U, Jakob PM, Nöth U. Iron oxide labelling of human mesenchymal stem cells in collagen hydrogels for articular cartilage repair. Biomaterials 29:1473-1483, 2008.
• Steinert AF, Weber M, Kunz M, Palmer GD, Nöth U, Evans CH, Murray MM. In situ IGF-1 gene delivery to cells emerging from injured anterior cruciate ligament. Biomaterials 29:904-916, 2008.

• Schütze N, Wagemanns R, Fiedler J, Mattes T, Jakob F, Brenner RE. CYR61/CCN1 and WISP3/CCN6 are chemoattractive ligands for human multipotent mesenchymal stroma cells. BMC Cell Biology 2007, 8:45.
• Cooper C, Jakob F, Chinn C, Martin-Mola E, Fardellone P, Adami S, Thalassinos NC, Melo-Gomes J, Torgerson D, Gibson A, Marin F. Fracture incidence and changes in quality of life in women with an inadequate clinical outcome from osteoporosis therapy: the Observational Study of Severe Osteoporosis (OSSO). Osteoporos Int. 2008 Apr;19(4):493-501. Epub 2007 Oct 30.
• Crockett JC*, Schütze N*, Tosh D, Jatzke S, Duthie A, Jakob F, Rogers MJ. The matricellular protein CYR61 inhibits osteoclastogenesis by a mechanism independent of alphavbeta3. Endocrinology 2007; 148(12):5761-8. *both authors contributed equally
• Li Y, Schilling T, Benisch P, Zeck S, Meissner-Weigl J, Schneider D, Limbert C, Seufert J, Kassem M, Schutze N, Jakob F, Ebert R. Effects of high glucose on mesenchymal stem cell proliferation and differentiation. Biophys Biochem Res Comm 2007; 9;363(1):209-15.
• Walther M, Mayer F, Kafka W, Schütze N. Effects of weak, low frequent pulsed electromagnetic fields (BEMER type) on gene expression of human mesenchymal stem cells and chondrocytes - an in vitro study. Electromagn Biol Med. 2007;26(3):179-90.
• Steinert AF, Palmer GD, Capito R, Hofstaetter JG, Pilapil C, Ghivizzani SC, Spector M, Evans CH. Genetically enhanced engineering of meniscus tissue using ex vivo delivery of transforming growth factor-beta 1 complementary deoxyribonucleic acid. Tissue Eng. 2007 Sep;13(9):2227-37.
• Schilling T, Küffner R, Klein-Hitpass L, Zimmer R, Jakob F, Schütze N. Microarray analyses of transdifferentiated mesenchymal stem cells. J Cell Biochem 2007;103(2):413-33.
• Evans CH, Palmer GD, Pascher A, Porter R, Kwong FN, Gouze E, Gouze JN, Liu F, Steinert A, Betz O, Betz V, Vrahas M, Ghivizzani SC. Facilitated endogenous repair: making tissue engineering simple, practical, and economical. Tissue Eng. 2007 Aug;13(8):1987-93.
• Nöth U, Rackwitz L, Heymer A, Weber M, Baumann B, Steinert A, Schütze N, Jakob F, Eulert J. Chondrogenic Differentiation of Human Mesenchymal Stem Cells in Collagen Type I Hydrogels. J Biomed Mat Res, 2007; 83A(3):623-635.
• Ince A, Schütze N, Karl N, Löhr JF, Eulert J. Gentamicin negatively influenced osteogenic function in vitro. Int Orthop. 2007; 31(2):223-8. Epub 2006 May 20.
• Baumann B, Seufert J, Rolf O, Jakob F, Goebel S, Eulert J, Rader CP. Upregulation of LITAF mRNA expression upon exposure to TiAlV and polyethylene wear particles in THP-1 macrophages / Hochregulation der LITAF-mRNA Expression nach Exposition gegenuber TiAlV- und Polyethylen-Abriebpartikeln in THP-1 Makrophagen. Biomed Tech (Berl). 2007; 52(2):200-7.
• Schilling T, Nöth U, Klein-Hitpass L, Jakob F, Schütze N. Plasticity in Adipogenesis and Osteogenesis of Human Mesenchymal Stem Cells. Mol Cell Endocrinol. 2007; 271(1-2):1-17.
• Ince A, Schütze N, Hendrich C, Jakob F, Eulert J, Löhr JF. Effect of polyhexanide and gentamycin on human osteoblasts and endothelial cells. Swiss Med Wkly. 2007; 137(9-10):139-45.

• Stehle J, Moore SM, Alaseirlis DA, Debski RE, McMahon PJ. Acromial morphology: Effects of suboptimal radiographs. J Shoulder Elbow Surg. 2006 Dec 11.
• Baumann B, Rolf O, Jakob F, Goebel S, Sterner T, Eulert J, Rader CP. Synergistic effects of mixed TiAlV and polyethylene wear particles on TNFalpha response in THP-1 macrophages. Biomed Tech (Berl). 2006;51(5-6):360-6.
• Jakob F, Marin F, Martin-Mola E, Torgerson D, Fardellone P, Adami S, Thalassinos NC, Sykes D, Melo-Gomes J, Chinn C, Nicholson T, Cooper C. Characterization of patients with an inadequate clinical outcome from osteoporosis therapy: the Observational Study of Severe Osteoporosis (OSSO). QJM. 2006 Aug;99(8):531-43.
• Radke S, Battmann A, Jatzke S, Eulert J, Jakob F, Schütze N. Expression of the angiomatrix and angiogenic proteins CYR61, CTGF, and VEGF in osteonecrosis of the femoral head. J Orthop Res. 2006 May;24(5):945-52.
• Murray MM, Forsythe B, Chen F, Lee SJ, Yoo JJ, Atala A, Steinert A. The effect of thrombin on ACL fibroblast interactions with collagen hydrogels. J Orthop Res. 2006 Mar;24(3):508-15.
• Kilger RH, Stehle J, Fisk JA, Thomas M, Miura K, Woo SL. Anatomical double-bundle anterior cruciate ligament reconstruction after valgus high tibial osteotomy: a biomechanical study. Am J Sports Med. 2006 Jun;34(6):961-7.
• Lienau J, Schell H, Epari DR, Schütze N, Jakob F, Duda GN, Bail HJ. CYR61 (CCN1) protein expression during fracture healing in an ovine tibial model and its relation to the mechanical fixation stability. J Orthop Res. 2006 Feb;24(2):254-62.
• Ebert R, Ulmer M, Zeck S, Meissner-Weigl J, Schneider D, Stopper H, Schupp N, Kassem M, Jakob F. Selenium supplementation restores the antioxidative capacity and prevents cell damage in bone marrow stromal cells in vitro. Stem Cells. 2006 May;24(5):1226-35.

• Laubner K, Kieffer TJ, Lam NT, Niu X, Jakob F, Seufert J. Inhibition of Preproinsulin Gene Expression by Leptin Induction of Suppressor of Cytokine Signaling 3 in Pancreatic {beta}-Cells. Diabetes. 2005;54(12):3410-3417.
• Nöth U, Schupp K, Heymer A, Kall S, Jakob F, Schütze N, Baumann B, Barthel T, Eulert J, Hendrich C. Anterior cruciate ligament constructs fabricated from human mesenchymal stem cells in a collagen type I hydrogel. Cytotherapy. 2005;7(5):447-55.
• Palmer GD, Steinert A, Pascher A, Gouze E, Gouze JN, Betz O, Johnstone B, Evans CH, Ghivizzani SC. Gene-induced chondrogenesis of primary mesenchymal stem cells in vitro. Mol Ther. 2005 Aug;12(2):219-28.
• Baumann B, Seufert J, Jakob F, Nöth U, Rolf O, Eulert J, Rader CP. Activation of NF-kappaB signalling and TNFalpha-expression in THP-1 macrophages by TiAlV- and polyethylene-wear particles. J Orthop Res. 2005 Nov;23(6):1241-8.
• Schütze N, Kunzi-Rapp K, Wagemanns R, Nöth U, Jatzke S, Jakob F. Expression, purification, and functional testing of recombinant CYR61/CCN1. Protein Expr Purif. 2005 Jul;42(1):219-25.
• Rolf O, Baumann B, Sterner T, Schütze N, Jakob F, Eulert J, Rader CP. Characterization of mode II-wear particles and cytokine response in a human macrophage-like cell culture. Biomed Tech (Berl). 2005 Jan-Feb;50(1-2):25-9.
• Schütze N, Nöth U, Schneidereit J, Hendrich C, Jakob F. Differential expression of CCN-family members in primary human bone marrow-derived mesenchymal stem cells during osteogenic, chondrogenic and adipogenic differentiation. Cell Commun Signal. 2005 Mar 17;3(1):5.

• Sterner T, Schütze N, Saxler G, Jakob F, Rader CP. [Effects of clinically relevant alumina ceramic, zirconia ceramic and titanium particles of different sizes and concentrations on TNF-alpha release in a human macrophage cell line] Biomed Tech (Berl). 2004 Dec;49(12):340-4.
• Abdallah BM, Haack-Sorensen M, Burns JS, Elsnab B, Jakob F, Hokland P, Kassem M. Maintenance of differentiation potential of human bone marrow mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene despite [corrected] extensive proliferation. Biochem Biophys Res Commun. 2005 Jan 21;326(3):527-38. Erratum in: Biochem Biophys Res Commun. 2005 Apr 22;329(4):1361.
• Kall S, Nöth U, Reimers K, Choi CY, Muehlberger T, Allmeling C, Jahn S, Heymer A, Vogt PM. [In vitro fabrication of tendon substitutes using human mesenchymal stem cells and a collagen type I gel] Handchir Mikrochir Plast Chir. 2004 Aug;36(4):205-11.
• Tuli R, Nandi S, Li WJ, Tuli S, Huang X, Manner PA, Laquerriere P, Nöth U, Hall DJ, Tuan RS. Human mesenchymal progenitor cell-based tissue engineering of a single-unit osteochondral construct.Tissue Eng. 2004 Jul-Aug;10(7-8):1169-79.
• Pascher A, Steinert AF, Palmer GD, Betz O, Gouze JN, Gouze E, Pilapil C, Ghivizzani SC, Evans CH, Murray MM. Enhanced repair of the anterior cruciate ligament by in situ gene transfer: evaluation in an in vitro model. Mol Ther. 2004 Aug;10(2):327-36.
• Baumann B, Rader CP, Seufert J, Nöth U, Rolf O, Eulert J, Jakob F. Effects of polyethylene and TiAlV wear particles on expression of RANK, RANKL and OPG mRNA. Acta Orthop Scand. 2004 Jun;75(3):295-302.
• Ebert R, Jovanovic M, Ulmer M, Schneider D, Meissner-Weigl J, Adamski J, Jakob F. Down-regulation by nuclear factor kappaB of human 25-hydroxyvitamin D3 1alpha-hydroxylase promoter. Mol Endocrinol. 2004 Oct;18(10):2440-50.
• Al-Taie OH, Uceyler N, Eubner U, Jakob F, Mork H, Scheurlen M, Brigelius-Flohe R, Schottker K, Abel J, Thalheimer A, Katzenberger T, Illert B, Melcher R, Köhrle J. Expression profiling and genetic alterations of the selenoproteins GI-GPx and SePP in colorectal carcinogenesis. Nutr Cancer. 2004;48(1):6-14.
• Absenger Y, Hess-Stumpp H, Kreft B, Kratzschmar J, Haendler B, Schütze N, Regidor PA, Winterhager E. Cyr61, a deregulated gene in endometriosis. Mol Hum Reprod. 2004 Jun;10(6):399-407.
• Pascher A, Palmer GD, Steinert A, Oligino T, Gouze E, Gouze JN, Betz O, Spector M, Robbins PD, Evans CH, Ghivizzani SC. Gene delivery to cartilage defects using coagulated bone marrow aspirate. Gene Ther. 2004 Jan;11(2):133-41.

• Al-Taie OH, Seufert J, Karvar S, Adolph C, Mörk H, Scheurlen M, Köhrle J, Jakob F. Selenium supplementation enhances low selenium levels and stimulates glutathione peroxidase activity in peripheral blood and distal colon mucosa in past and present carriers of colon adenomas. Nutr Cancer. 2003;46(2):125-30.
• Nöth U, Tuli R, Seghatoleslami R, Howard M, Shah A, Hall DJ, Hickok NJ, Tuan RS. Activation of p38 and Smads mediates BMP-2 effects on human trabecular bone-derived osteoblasts. Exp Cell Res. 2003 Nov 15;291(1):201-11.
• Steinert A, Weber M, Dimmler A, Julius C, Schütze N, Nöth U, Cramer H, Eulert J, Zimmermann U, Hendrich C. Chondrogenic differentiation of mesenchymal progenitor cells encapsulated in ultrahigh-viscosity alginate. J Orthop Res. 2003 Nov;21(6):1090-7.
• Fassnacht M, Hahner S, Hansen IA, Kreutzberger T, Zink M, Adermann K, Jakob F, Troppmair J, Allolio B. N-terminal proopiomelanocortin acts as a mitogen in adrenocortical tumor cells and decreases adrenal steroidogenesis. J Clin Endocrinol Metab. 2003 May;88(5):2171-9.
• Mörk H, Scheurlen M, Al-Taie O, Zierer A, Kraus M, Schottker K, Jakob F, Köhrle J. Glutathione peroxidase isoforms as part of the local antioxidative defense system in normal and Barrett's esophagus. Int J Cancer. 2003 Jun 20;105(3):300-4.

• Barthel T, Baumann B, Nöth U, Eulert J. Prophylaxis of heterotopic ossification after total hip arthroplasty: a prospective randomized study comparing indomethacin and meloxicam. Acta Orthop Scand. 2002 Dec;73(6):611-4.
• Nöth U, Osyczka AM, Tuli R, Hickok NJ, Danielson KG, Tuan RS. Multilineage mesenchymal differentiation potential of human trabecular bone-derived cells. J Orthop Res. 2002 Sep;20(5):1060-9.
• Osyczka AM, Nöth U, O'Connor J, Caterson EJ, Yoon K, Danielson KG, Tuan RS. Multilineage differentiation of adult human bone marrow progenitor cells transduced with human papilloma virus type 16 E6/E7 genes. Calcif Tissue Int. 2002 Nov;71(5):447-58.
• Al-Taie OH, Seufert J, Mork H, Treis H, Mentrup B, Thalheimer A, Starostik P, Abel J, Scheurlen M, Köhrle J, Jakob F. A complex DNA-repeat structure within the Selenoprotein P promoter contains a functionally relevant polymorphism and is genetically unstable under conditions of mismatch repair deficiency. Eur J Hum Genet. 2002 Sep;10(9):499-504.
• Viereck V, Siggelkow H, Tauber S, Raddatz D, Schütze N, Hufner M. Differential regulation of Cbfa1/Runx2 and osteocalcin gene expression by vitamin-D3, dexamethasone, and local growth factors in primary human osteoblasts. J Cell Biochem. 2002;86(2):348-56.
• Rader ChP, Baumann B, Rolf O, Radke S, Hendrich Ch, Schütze N, Seufert J, Jakob F. Detection of differentially expressed genes in particle disease using array-filter analysis.Biomed Tech (Berl). 2002 May;47(5):111-6.
• Osyczka AM, Noth U, Danielson KG, Tuan RS. Different osteochondral potential of clonal cell lines derived from adult human trabecular bone. Ann N Y Acad Sci. 2002 Jun;961:73-7.
• Weber M, Steinert A, Jork A, Dimmler A, Thurmer F, Schütze N, Hendrich C, Zimmerman U. Formation of cartilage matrix proteins by BMP-transfected murine mesenchymal stem cells encapsulated in a novel class of alginates. Biomaterials. 2002 May;23(9):2003-13.
• Merklein F, Dimmler A, Steinert A, Schütze N, Noth U, Papadopoulos T, Eulert J, Thull R, Hendrich C. [Standardized testing of skeletal implant surfaces with an osteoblast cell culture system. IV. Specific gene expression during differentiation] Biomed Tech (Berl). 2002 Jan-Feb;47(1-2):26-31.
• Nöth U, Tuli R, Osyczka AM, Danielson KG, Tuan RS. In vitro engineered cartilage constructs produced by press-coating biodegradable polymer with human mesenchymal stem cells. Tissue Eng. 2002 Feb;8(1):131-44.
• Hendrich C, Nöth U, Stahl U, Merklein F, Rader CP, Schütze N, Thull R, Tuan RS, Eulert J. Testing of skeletal implant surfaces with human fetal osteoblasts. Clin Orthop Relat Res. 2002 Jan;(394):278-89.

• Zimmermann U, Thurmer F, Jork A, Weber M, Mimietz S, Hillgartner M, Brunnenmeier F, Zimmermann H, Westphal I, Fuhr G, Nöth U, Haase A, Steinert A, Hendrich C. A novel class of amitogenic alginate microcapsules for long-term immunoisolated transplantation. Ann N Y Acad Sci. 2001 Nov;944:199-215.
• Seufert J, Ebert K, Muller J, Eulert J, Hendrich C, Werner E, Schütze N, Schulz G, Kenn W, Richtmann H, Palitzsch KD, Jakob F. Octreotide therapy for tumor-induced osteomalacia. N Engl J Med. 2001 Dec 27;345(26):1883-8.
• Steinert AF, Hendrich C, Zimmermann U. [Tissue engineering of cartilage replacement tissue in an improved alginate matrix] Z Orthop Ihre Grenzgeb. 2001 Sep-Oct;139(5):M94-5.
• Bauer WO, Nanda I, Beck G, Schmid M, Jakob F. Human puromycin-sensitive aminopeptidase: cloning of 3' UTR, evidence for a polymorphism at a.a. 140 and refined chromosomal localization to 17q21. Cytogenet Cell Genet. 2001;92(3-4):221-4.
• Schütze N, Rücker N, Muller J, Adamski J, Jakob F. 5' flanking sequence of the human immediate early responsive gene ccn1 (cyr61) and mapping of polymorphic CA repeat sequence motifs in the human ccn1 (cyr61) locus. Mol Pathol. 2001 Jun;54(3):170-5.

• Steinert A, Hendrich C, Merklein F, Rader CP, Schütze N, Thull R, Eulert J. [Standardized testing of bone implant surfaces with an osteoblast cell culture cyste. III. PVD hard coatings and Ti6Al4V] Biomed Tech (Berl). 2000 Dec;45(12):349-55.
• Altvater T, Hendrich C, Nöth U, Rader CP, Stach R, Schütze N, Eulert J, Thull R. [Cytotoxicity study of high gold content Degutan surfaces of various degrees of roughness with fibroblasts (BALB 3T3) and osteoblasts (hFOB 1.19)] Biomed Tech (Berl). 2000 Sep;45(9):238-42.
• Mörk H, al-Taie OH, Bahr K, Zierer A, Beck C, Scheurlen M, Jakob F, Köhrle J. Inverse mRNA expression of the selenocysteine-containing proteins GI-GPx and SeP in colorectal adenomas compared with adjacent normal mucosa. Nutr Cancer. 2000;37(1):108-16.
• Kenn W, Eck M, Allolio B, Jakob F, Illg A, Marx A, Mueller-Hermelink HK, Hahn D. Erdheim-Chester disease: evidence for a disease entity different from Langerhans cell histiocytosis? Three cases with detailed radiological and immunohistochemical analysis. Hum Pathol. 2000 Jun;31(6):734-9.
• Lechner A, Schütze N, Siggelkow H, Seufert J, Jakob F. The immediate early gene product hCYR61 localizes to the secretory pathway in human osteoblasts. Bone. 2000 Jul;27(1):53-60.

Orginalarbeiten 1999

• Schütze N, Fritsche J, Ebert-Dumig R, Schneider D, Köhrle J, Andreesen R, Kreutz M, Jakob F. The selenoprotein thioredoxin reductase is expressed in peripheral blood monocytes and THP1 human myeloid leukemia cells--regulation by 1,25-dihydroxyvitamin D3 and selenite. Biofactors. 1999;10(4):329-38.
• Rader CP, Sterner T, Jakob F, Schütze N, Eulert J. Cytokine response of human macrophage-like cells after contact with polyethylene and pure titanium particles. J Arthroplasty. 1999 Oct;14(7):840-8.
• Rader CP, Baumann B, Sterner T, Rolf O, Hendrich C, Schütze N, Jakob F. [TNF-alpha secretion by human macrophage-like cells in response to wear particles and its modification by drugs] Biomed Tech (Berl). 1999 May;44(5):135-41.
• Nöth U, Hendrich C, Merklein F, Altvater T, Rader CP, Schütze N, Eulert J, Thull R. [Standardized testing of bone implant surfaces with an osteoblast cell culture system. II. Titanium surfaces of different degrees of roughness] Biomed Tech (Berl). 1999 Jan-Feb;44(1-2):6-11.
  

Orginalarbeiten 1998

• Merklein F, Hendrich C, Nöth U, Kochinki G, Rader CP, Schütze N, Thull R, Eulert J. [Standardized tests of bone implant surfaces with an osteoblast cell culture system. I. Orthopedic standard materials] Biomed Tech (Berl). 1998 Dec;43(12):354-9.
• Mörk H, Lex B, Scheurlen M, Dreher I, Schütze N, Köhrle J, Jakob F. Expression pattern of gastrointestinal selenoproteins--targets for selenium supplementation. Nutr Cancer. 1998;32(2):64-70.
• Mörk H, Barth T, Kreipe HH, Kraus M, Al-Taie O, Jakob F, Scheurlen M. Reconstitution of squamous epithelium in Barrett's oesophagus with endoscopic argon plasma coagulation: a prospective study. Scand J Gastroenterol. 1998 Nov;33(11):1130-4.
• Winzer R, Schmutzler C, Jakobs TC, Ebert R, Rendl J, Reiners C, Jakob F, Köhrle J. Reverse transcriptase-polymerase chain reaction analysis of thyrocyte-relevant genes in fine-needle aspiration biopsies of the human thyroid. Thyroid. 1998 Nov;8(11):981-7.
• Schütze N, Bachthaler M, Lechner A, Köhrle J, Jakob F. Identification by differential display PCR of the selenoprotein thioredoxin reductase as a 1 alpha,25(OH)2-vitamin D3-responsive gene in human osteoblasts--regulation by selenite. Biofactors. 1998;7(4):299-310.
• Dreher I, Schütze N, Baur A, Hesse K, Schneider D, Köhrle J, Jakob F. Selenoproteins are expressed in fetal human osteoblast-like cells. Biochem Biophys Res Commun. 1998 Apr 7;245(1):101-7.
• Schütze N, Lechner A, Groll C, Siggelkow H, Hüfner M, Köhrle J, Jakob F. The human analog of murine cystein rich protein 61 [correction of 16] is a 1alpha,25-dihydroxyvitamin D3 responsive immediate early gene in human fetal osteoblasts: regulation by cytokines, growth factors, and serum. Endocrinology. 1998 Apr;139(4):1761-70.
  

Orginalarbeiten 1997

• Nöth U, Hendrich C, Scheddin D, Altvater T, Eulert J, Thull R. [Effect of titanium surfaces of various roughness on cell proliferation, cell differentiation and protein synthesis of human fetal osteoblasts (hFOB 1.19)] Biomed Tech (Berl). 1997;42 Suppl:367-8.
• Jakob F, Siggelkow H, Homann D, Köhrle J, Adamski J, Schütze N. Local estradiol metabolism in osteoblast- and osteoclast-like cells. J Steroid Biochem Mol Biol. 1997 Apr;61(3-6):167-74.
• Dreher I, Schmutzler C, Jakob F, Köhrle J. Expression of selenoproteins in various rat and human tissues and cell lines. J Trace Elem Med Biol. 1997 Jun;11(2):83-91.
• Mörk H, Jakob F, al-Taie O, Gassel AM, Scheurlen M. Primary biliary cirrhosis and gastric carcinoid: a rare association? J Clin Gastroenterol. 1997 Jun;24(4):270-3.
• Adamski J, Leenders F, Carstensen JF, Kaufmann M, Markus MM, Husen B, Tesdorpf JG, Seedorf U, de Launoit Y, Jakob F. Steroids, fatty acyl-CoA, and sterols are substrates of 80-kDa multifunctional protein. Steroids. 1997 Jan;62(1):159-63.
  

Orginalarbeiten 1996

• Hendrich C, Geyer M, Scheddin D, Schütze N, Eulert J, Thull R. [A new osteoblast cell culture system for standardized testing of biomaterials] Biomed Tech (Berl). 1996 Oct;41(10):278-83.
• Carstensen JF, Tesdorpf JG, Kaufmann M, Markus MM, Husen B, Leenders F, Jakob F, de Launoit Y, Adamski J. Characterization of 17 beta-hydroxysteroid dehydrogenase IV. J Endocrinol. 1996 Sep;150 Suppl:S3-12.
• Seibold F, Klein R, Jakob F. Polymyositis, alopecia universalis, and primary sclerosing cholangitis in a patient with Crohn's disease. J Clin Gastroenterol. 1996 Sep;23(2):121-4.
• Boege F, Straub T, Kehr A, Boesenberg C, Christiansen K, Andersen A, Jakob F, Köhrle J. Selected novel flavones inhibit the DNA binding or the DNA religation step of eukaryotic topoisomerase I. J Biol Chem. 1996 Jan 26;271(4):2262-70.
  

Orginalarbeiten 1995

• Jakob F, Homann D, Adamski J. Expression and regulation of aromatase and 17 beta-hydroxysteroid dehydrogenase type 4 in human THP 1 leukemia cells. J Steroid Biochem Mol Biol. 1995 Dec;55(5-6):555-63.
• Schütze N, Oursler MJ, Nolan J, Riggs BL, Spelsberg TC. Zeolite A inhibits osteoclast-mediated bone resorption in vitro. J Cell Biochem. 1995 May;58(1):39-46.
• Jakob F, Homann D, Seufert J, Schneider D, Köhrle J. Expression and regulation of aromatase cytochrome P450 in THP 1 human myeloid leukaemia cells. Mol Cell Endocrinol. 1995 Apr 28;110(1-2):27-33.
  

Orginalarbeiten 1994

• Schötze N, Vollmer G, Knuppen R. Catecholestrogens are agonists of estrogen receptor dependent gene expression in MCF-7 cells. J Steroid Biochem Mol Biol. 1994 Apr;48(5-6):453-61.
• Jakob F, Seufert J, Sarrazin C, Schneider D, Köhrle J, Tony HP. Topoisomerase I-inhibition enhances vitamin D-responsive expression of the receptor for lipopolysaccharide binding protein CD 14. Biochem Biophys Res Commun. 1994 Mar 15;199(2):531-9.
• Schütze N, Vollmer G, Wünsche W, Grote A, Feit B, Knuppen R. Binding of 2-hydroxyestradiol and 4-hydroxyestradiol to the estrogen receptor of MCF-7 cells in cytosolic extracts and in nuclei of intact cells. Exp Clin Endocrinol. 1994;102(5):399-408.
• Schütze N, Schneider MR, Knuppen R, Vollmer G. Tamoxifen and ZK 119010 exert mixed agonistic and antagonistic effects on pS2 expression in MCF-7 cells. Cancer Detect Prev. 1994;18(6):479-83.
  

Orginalarbeiten 1993

• Jakob F, Seufert J, Haack D, Schroder K, Ludwig J, Rendl J, Vecsei P. [Unilateral autonomous aldosterone production in hyperaldosteronism suppressible by dexamethasone] Dtsch Med Wochenschr. 1993 Dec 17;118(50):1837-43.
• Schütze N, Vollmer G, Tiemann I, Geiger M, Knuppen R. Catecholestrogens are MCF-7 cell estrogen receptor agonists. J Steroid Biochem Mol Biol. 1993 Dec;46(6):781-9.
• Thole HH, Jakob F. Characterization of five monoclonal antibodies raised against domain E of the porcine estradiol receptor. Exp Clin Endocrinol. 1993;101(2):112-8.
  

Orginalarbeiten 1992

• Schütze N, Kraft V, Deerberg F, Winking H, Meitinger D, Ebert K, Knuppen R, Vollmer G. Functions of estrogens and anti-estrogens in the rat endometrial adenocarcinoma cell lines RUCA-I and RUCA-II. Int J Cancer. 1992 Dec 2;52(6):941-9.
• Jakob F, Tony HP, Schneider D, Thole HH. Immunological detection of the oestradiol receptor protein in cell lines derived from the lymphatic system and the haematopoietic system: variability of specific hormone binding in vitro. J Endocrinol. 1992 Sep;134(3):397-404.
• Jakob F, Gieseler F, Tresch A, Hammer S, Seufert J, Schneider D. Kinetics of nuclear translocation and turnover of the vitamin D receptor in human HL60 leukemia cells and peripheral blood lymphocytes--coincident rise of DNA-relaxing activity in nuclear extracts. J Steroid Biochem Mol Biol. 1992 Mar;42(1):11-6.
• Sierralta WD, Jakob F, Thole H, Engel P, Jungblut PW. Estradiol-promoted accumulation of receptor in nuclei of porcine endometrium cells. Immunogold electron microscopy of resting and estradiol-stimulated cells. Receptor. 1992 Spring;2(1):29-37.