INSU Cor Fall Kontroll Studie
Prof. Peter Heuschmann, Prof. Jens Volkmann
Felipe Montellano, Daniel Mackenrodt, Kathrin Ungethüm
Prof. Dr. Stefan Störk, Dr. Caroline Morbach, Daniel Mackenrodt, Dr. Katharina Gabriel, Viktoria Rücker, Anika Quilitzsch, Timo Ludwig, PD Dr. Peter Kraft, Dr. Felix Fluri, Prof. Dr. M. Pham, Ahmed Elhfnawy
Federal Ministry of Education and Research within the Comprehensive Heart Failure Center.
Ongoing; since April 2017
Cardiac diseases are established risk factors for ischemic stroke. Animal experiments and observational studies indicate a bidirectional relationship between cardiac disease and ischemic stroke and that cardiac dysfunction and cardiac events occur also after an ischemic stroke. The INSU Cor (Insular - Non - Insular Stroke Underlying Cardiac Failure) study investigates the development of new systolic dysfunction in patients with ischemic stroke and lesions in the insular cortex. Within this case control study, stroke patients of the University Hospital Würzburg are examined for a new cardiac dysfunction during their hospital stay and in the further course. This is done by means of further blood samples, more precise clinical examinations, as well as interviews about cardiovascular and accompanying diseases that are associated with ischemic stroke. After the baseline examination, three follow-up examinations (after 1, 4 and 12 weeks) are carried out. These include echocardiography, clinicial examination (eg heart sounds, blood pressure fluctuations) , interviews (eg risk factors, concomitant diseases, medication) ) and collection of blood samples. The main focus of the case control study is the description of the development of new systolic dysfunction in a total of 180 patients with ischemic stroke and either one or none lesion in the insular cortex. The study is a collaborative project of the Institute for Clinical Epidemiology and Biometry (ICE-B) of the University of Würzburg and the Department of Neurology at the University Hospital of Würzburg within the Comprehensive Heart Failure Center.