Prof. Dr. Deckert, Jürgen (Senior Professor)
Prof. Dr. Jürgen Deckert
Petrinistrasse 33a
Phone:
+49 931 31-82070
Fax:
+49 931 31-820700
Email:
Deckert_J@ukw.de
kurzer Lebenslauf
seit 2024 | Senior Professor, Institut für Klinische Epidemiologie und Biometrie, Julius-Maximilians-Universität Würzburg | ||
2017-2023 | Prodekan Internationalisierung | ||
2010-2013 | Studiendekan | ||
2008-2020 | Standortsprecher und PI SFB TRR 58 Furcht, Angst und Angsterkrankungen | ||
2006-2024 | Professor für Psychiatrie (W3) und Direktor Klinik und Poliklinik für Psychiatrie, Psychosomatik und Psychotherapie, Julius-Maximilians-Universität Würzburg | ||
2004-2006 | Professor für Molekulare Psychiatrie (C3) und Stellvertretender Direktor, Wilhelms-Universität Münster | ||
1999-2004 | Leitender Oberarzt, Klinik für Psychiatrie und Psychotherapie, Wilhelms-Universität Münster | ||
1997 | Venia legendi in Psychiatrie, Julius-Maximilians-Universität Würzburg | ||
1992/2002 | Facharztanerkennung Psychiater/Psychiater und Psychotherapeut | ||
1994-1996 | DFG Habilitationsstipendium, Humangenetik, Friedrich-Wilhelms Universität Bonn | ||
1991-1992 | Assistenzarzt, Klinik für Neurologie, Ruhr Universität | ||
1988-1998 | Assistenzarzt und Oberarzt, Klinik und Poliklinik für Psychiatrie und Psychotherapie, Julius-Maximilians-Universität Würzburg | ||
1985-1988 | DFG Ausbildungsstipendium, NIMH Bethesda, USA | ||
1985 | Promotion Dr. med., summa cum laude, Julius-Maximilians-Universität Würzburg | ||
1977-1984 | Medizinstudium, Julius-Maximilians-Universität Würzburg |
wissenschaftliche Schwerpunkte
Psychiatrische Genetik, Psychiatrische Kohortenstudien, Klinische Studien
Hauptpublikationen der letzten Jahre
2024[ to top ]
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Validation of the predictive value of BDNF -87 methylation for antidepressant treatment success in severely depressed patients-a randomized rater-blinded trial. Trials. 2024;25(1):247..
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Definition of the Post-COVID syndrome using a symptom-based Post-COVID score in a prospective, multi-center, cross-sectoral cohort of the German National Pandemic Cohort Network (NAPKON). Infection [Internet]. 2024;. Available from: https://www.ncbi.nlm.nih.gov/pubmed/38587752.
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Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder. Nat Genet. 2024;56(5):792-808..
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Risk Phenotypes, Comorbidities, Pharmacotherapy, and Electroconvulsive Therapy (ECT) in a Cohort with Difficult-to-Treat Depression in Comparison to an Unmedicated Control Group. Pharmacopsychiatry. 2024;57(4):191-203..
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[Genetic diagnostics of mental health disorders in adulthood]. Nervenarzt. 2024;..
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Prognostic Utility of Pericardial Effusion in the General Population: Findings From the STAAB Cohort Study. J Am Heart Assoc. 2024;13(12):e035549..
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The Relevance of Integrating CYP2C19 Phenoconversion Effects into Clinical Pharmacogenetics. Pharmacopsychiatry. 2024;57(2):69-77..
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Frequencies of CYP2C19 and CYP2D6 gene variants in a German inpatient sample with mood and anxiety disorders. World J Biol Psychiatry. 2024;25(4):214-21..
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Potential causal association between gut microbiome and posttraumatic stress disorder. Transl Psychiatry. 2024;14(1):67..
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Lack of evidence for predictive utility from resting state fMRI data for individual exposure-based cognitive behavioral therapy outcomes: A machine learning study in two large multi-site samples in anxiety disorders. Neuroimage. 2024;295:120639..
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Intermittent theta burst stimulation of the left dorsolateral prefrontal cortex has no additional effect on the efficacy of virtual reality exposure therapy for acrophobia. A randomized double-blind placebo-controlled study. Behav Brain Res. 2024;476:115232..
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Heart rate variability, interoceptive accuracy and functional connectivity in middle-aged and older patients with depression. J Psychiatr Res. 2024;170:122-9..
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Predictors of non-recovery from fatigue and cognitive deficits after COVID-19: a prospective, longitudinal, population-based study. eClinicalMedicine [Internet]. 2024;69:102456. Available from: https://www.sciencedirect.com/science/article/pii/S258953702400035X.
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Childhood Trauma and Somatic and Mental Illness in Adulthood. Dtsch Arztebl International [Internet]. 2024;121(1):1-8. Available from: https://www.aerzteblatt.de/int/article.asp?id=236520.
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Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood. Science. 2024;384(6698):eadh3707..
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Resting-state functional connectivity in anxiety disorders: a multicenter fMRI study. Mol Psychiatry. 2024;..
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Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling. medRxiv. 2024;..
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Elevated accuracy in recognition of subliminal happy facial expressions in patients with panic disorder after psychotherapy. Front Psychiatry. 2024;15:1375751..
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Depression and fatigue six months post-COVID-19 disease are associated with overlapping symptom constellations: A prospective, multi-center, population-based cohort study. J Affect Disord. 2024;352:296-305..
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When a test is more than just a test: Findings from patient interviews and survey in the trial of a technology to measure antidepressant medication response (the PReDicT Trial). Compr Psychiatry. 2024;132:152467..
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Determinants and reference values of the 6-min walk distance in the general population-results of the population-based STAAB cohort study. Clin Res Cardiol. 2024;..
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Definitions and symptoms of the post-COVID syndrome: an updated systematic umbrella review. Eur Arch Psychiatry Clin Neurosci. 2024;..
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A genome-wide association meta-analysis of all-cause and vascular dementia. consortium MVCID, editor. Alzheimers Dement [Internet]. 2024;20(9):5973-95. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39046104.
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[TDM of antidepressants shortens length of hospital stay : Reduction in length of stay by routine therapeutic drug monitoring of antidepressants on admission to hospital]. Nervenarzt. 2024;95(7):660-2..
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2023[ to top ]
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The application of virtual reality exposure versus relaxation training in music performance anxiety: a randomized controlled study. BMC Psychiatry. 2023;23(1):555..
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Effect of CYP2D6 pharmacogenetic phenotype and phenoconversion on serum concentrations of antidepressants and antipsychotics: a retrospective cohort study. Int J Clin Pharm. 2023;45(5):1107-1..
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The effects of everyday-life social interactions on anxiety-related autonomic responses differ between men and women. Sci Rep. 2023;13(1):9498..
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Persistent symptoms and risk factors predicting prolonged time to symptom-free after SARS‑CoV‑2 infection: an analysis of the baseline examination of the German COVIDOM/NAPKON-POP cohort. Infection. 2023;:1-16..
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Prospective single-center study of health-related quality of life after COVID-19 in ICU and non-ICU patients. Sci Rep. 2023;13(1):6785..
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Differential network interactions between psychosocial factors, mental health, and health-related quality of life in women and men. Sci Rep. 2023;13(1):11642..
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[Quality of Life and Experienced Distress of Patients Suspected of having a Rare (Chronic) Health Condition - Initial Findings from the ZSE-DUO Study]. Psychother Psychosom Med Psychol. 2023;73(1):9-15..
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The Relationship of Attention-Deficit/Hyperactivity Disorder With Posttraumatic Stress Disorder: A Two-Sample Mendelian Randomization and Population-Based Sibling Comparison Study. Biol Psychiatry. 2023;93(4):362-9..
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Generalised anxiety and panic symptoms in the German National Cohort (NAKO). World J Biol Psychiatry. 2023;24(10):881-96..
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Prevalence of COVID-19 and Psychotropic Drug Treatment in Psychiatric In-patients in Germany in 2020: Results from a Nationwide Pilot Survey. Pharmacopsychiatry. 2023;56(6):227-38..
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Effective-and Tolerable: Acceptance and Side Effects of Intensified Exposure for Anxiety Disorders. Behav Ther. 2023;54(3):427-43..
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Discovery of 95 PTSD loci provides insight into genetic architecture and neurobiology of trauma and stress-related disorders. medRxiv. 2023;..
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The assessment of childhood maltreatment and its associations with affective symptoms in adulthood: Results of the German National Cohort (NAKO). World J Biol Psychiatry. 2023;24(10):897-908..
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Deep phenotyping as a contribution to personalized depression therapy: the GEParD and DaCFail protocols. J Neural Transm (Vienna). 2023;130(5):707-22..
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Effect of the addition of a mental health specialist for evaluation of undiagnosed patients in centres for rare diseases (ZSE-DUO): a prospective, controlled trial with a two-phase cohort design. EClinicalMedicine. 2023;65:102260..
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Author Correction: Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores. Nat Commun. 2023;14(1):716..
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45 years German Society of Biological Psychiatry (DGBP). J Neural Transm (Vienna). 2023;130(9):1091-6..
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Effects of Anxious Depression on Antidepressant Treatment Response. Int J Mol Sci. 2023;24(24)..
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2022[ to top ]
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ENIGMA-anxiety working group: Rationale for and organization of large-scale neuroimaging studies of anxiety disorders. Hum Brain Mapp. 2022;43(1):83-112..
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Association of polygenic risk scores, traumatic life events and coping strategies with war-related PTSD diagnosis and symptom severity in the South Eastern Europe (SEE)-PTSD cohort. J Neural Transm (Vienna). 2022;129(5-6):661-74..
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Rare copy number variation in posttraumatic stress disorder. Mol Psychiatry. 2022;27(12):5062-9..
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Construction and Validation of a Scale to Measure Loneliness and Isolation During Social Distancing and Its Effect on Mental Health. Front Psychiatry. 2022;13:798596..
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Factors associated with dropout in the longitudinal Vogel study of cognitive decline. Eur J Neurosci. 2022;56(9):5587-600..
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Reduced parietal activation in participants with mild cognitive impairments during visual-spatial processing measured with functional near-infrared spectroscopy. J Psychiatr Res. 2022;146:31-42..
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Fear conditioning and stimulus generalization in association with age in children and adolescents. Eur Child Adolesc Psychiatry. 2022;31(10):1581-90..
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Rationale, Mission and Vision for a National Centre of Affective Disorders in Germany. Pharmacopsychiatry. 2022;55(2):65-72..
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Dual guidance structure for evaluation of patients with unclear diagnosis in centers for rare diseases (ZSE-DUO): study protocol for a controlled multi-center cohort study. Orphanet Journal of Rare Diseases [Internet]. 2022;17(1):47. Available from: https://doi.org/10.1186/s13023-022-02176-1.
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[ZSE-DUO - dual guidance structure at the centre for rare diseases]. Inn Med (Heidelb). 2022;63(7):791-7..
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Effects of Pharmacokinetic Gene Variation on Therapeutic Drug Levels and Antidepressant Treatment Response. Pharmacopsychiatry. 2022;55(5):246-54..
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Measurement invariance testing of longitudinal neuropsychiatric test scores distinguishes pathological from normative cognitive decline and highlights its potential in early detection research. J Neuropsychol. 2022;16(2):324-52..
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Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information. Biol Psychiatry. 2022;91(7):626-3..
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New insights into the genetic etiology of Alzheimer’s disease and related dementias. Nat Genet. 2022;54(4):412-36..
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Lifetime and current depression in the German National Cohort (NAKO). World J Biol Psychiatry. 2022;:1-16..
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2021[ to top ]
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Social buffering of human fear is shaped by gender, social concern, and the presence of real vs virtual agents. Transl Psychiatry. 2021;11(1):641..
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Review and Consensus on Pharmacogenomic Testing in Psychiatry. Pharmacopsychiatry. 2021;54(1):5-17..
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Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression. Mol Psychiatry. 2021;26(8):4179-90..
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Prevalence and determinants of the precursor stages of heart failure: results from the population-based STAAB cohort study. European Journal of Preventive Cardiology [Internet]. 2021;28(9):924-3. Available from: https://doi.org/10.1177/2047487320922636.
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Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores. Nat Commun. 2021;12(1):3417..
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Antipsychotics in routine treatment are minor contributors to QT prolongation compared to genetics and age. J Psychopharmacol. 2021;35(9):1127-33..
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Vagal control of the heart decreases during increasing imminence of interoceptive threat in patients with panic disorder and agoraphobia. Sci Rep. 2021;11(1):7960..
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Impaired fear learning and extinction, but not generalization, in anxious and non-anxious depression. J Psychiatr Res. 2021;135:294-301..
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Impact of Body Mass Index on Serum Concentrations of Antidepressants and Antipsychotics. Ther Drug Monit. 2021;43(2):286-91..
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BNST and amygdala activation to threat: Effects of temporal predictability and threat mode. Behav Brain Res. 2021;396:112883..
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Stress impairs response to antidepressants via HPA axis and immune system activation. Brain Behav Immun. 2021;93:132-40..
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Seroprävalenz von COVID-19 und psychosoziale Auswirkungen in der Allgemeinbevölkerung: Ergebnisse des STAAB-COVID-One Programms. Das Gesundheitswesen. 2021;83(12):965-7..
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Transfer of exposure therapy effects to a threat context not considered during treatment in patients with panic disorder and agoraphobia: Implications for potential mechanisms of change. Behav Res Ther. 2021;142:103886..
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Psychological trauma and the genetic overlap between posttraumatic stress disorder and major depressive disorder. Psychol Med. 2021;52(16):1-10..
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Efficacy of temporally intensified exposure for anxiety disorders: A multicenter randomized clinical trial. Depress Anxiety. 2021;38(11):1169-81..
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The cognitive anxiety sensitivity treatment (CAST) in anxiety prevention - Focus on separation anxiety and interoception. Eur Neuropsychopharmacol. 2021;53:104-13..
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The role of pharmacogenetics in the treatment of anxiety disorders and the future potential for targeted therapeutics. Expert Opin Drug Metab Toxicol. 2021;17(11):1249-60..
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Reducing Generalization of Conditioned Fear: Beneficial Impact of Fear Relevance and Feedback in Discrimination Training. Front Psychol. 2021;12:665711..
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Serotonin transporter genotype modulates resting state and predator stress-induced amygdala perfusion in mice in a sex-dependent manner. PLoS One. 2021;16(2):e0247311..
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Corona Health—A Study- and Sensor-Based Mobile App Platform Exploring Aspects of the COVID-19 Pandemic. International Journal of Environmental Research and Public Health. 2021;18(14):7395..
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The clinical effectiveness of using a predictive algorithm to guide antidepressant treatment in primary care (PReDicT): an open-label, randomised controlled trial. Neuropsychopharmacology. 2021;46(7):1307-14..
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Patients with higher vitamin D levels show stronger improvement of self-reported depressive symptoms in psychogeriatric day-care setting. J Neural Transm (Vienna). 2021;128(8):1233-8..
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2020[ to top ]
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An investigation of genetic variability of DNA methyltransferases DNMT3A and 3B does not provide evidence for a major role in the pathogenesis of panic disorder and dimensional anxiety phenotypes. J Neural Transm (Vienna). 2020;127(11):1527-3..
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Neuronal correlates of the visual-spatial processing measured with functional near-infrared spectroscopy in healthy elderly individuals. Neuropsychologia. 2020;148:107650..
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Therapeutic Drug Monitoring of Antidepressants for the Treatment of Chronic Musculoskeletal Pain With and Without Depression. Ther Drug Monit. 2020;42(6):893-901..
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Extent of cortisol suppression at baseline predicts improvement in HPA axis function during antidepressant treatment. Psychoneuroendocrinology. 2020;114:104590..
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Anxiety risk SNPs on chromosome 2 modulate arousal in children in a fear generalization paradigm. Eur Child Adolesc Psychiatry. 2020;29(9):1301-10..
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The modulating impact of cigarette smoking on brain structure in panic disorder: a voxel-based morphometry study. Soc Cogn Affect Neurosci. 2020;15(8):849-5..
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Three Questions to Consider Before Applying Ecological Momentary Interventions (EMI) in Psychiatry. Front Psychiatry. 2020;11:333..
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Anxiety and Startle Phenotypes in Glrb Spastic and Glra1 Spasmodic Mouse Mutants. Front Mol Neurosci. 2020;13:152..
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Affective temperaments (TEMPS-A) in panic disorder and healthy probands: Genetic modulation by 5-HTT variation. World J Biol Psychiatry. 2020;21(10):790-6..
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The mere physical presence of another person reduces human autonomic responses to aversive sounds. Proc Biol Sci. 2020;287(1919):20192241..
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Generalization of Conditioned Contextual Anxiety and the Modulatory Effects of Anxiety Sensitivity. Neurotherapeutics. 2020;17(3):1239-52..
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Serotonergic influence on depressive symptoms and trait anxiety is mediated by negative life events and frontal activation in children and adolescents. Eur Child Adolesc Psychiatry. 2020;29(5):691-706..
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Nortriptyline serum concentration as a predictor for cardiac risk in amitriptyline-treated patients. Eur J Clin Pharmacol. 2020;76(1):73-80..
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DNA hypomethylation of the Krüppel-like factor 11 (KLF11) gene promoter: a putative biomarker of depression comorbidity in panic disorder and of non-anxious depression?. J Neural Transm (Vienna). 2020;127(11):1539-46..
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Extending the vulnerability-stress model of mental disorders: three-dimensional NPSR1 × environment × coping interaction study in anxiety. Br J Psychiatry. 2020;217(5):645-50..
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Higher venlafaxine serum concentrations necessary for clinical improvement? Time to re-evaluate the therapeutic reference range of venlafaxine. J Psychopharmacol. 2020;34(10):1105-11..
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Pathological Concentration of C-reactive Protein is Correlated to Increased Concentrations of Quetiapine, But Not of Risperidone, Olanzapine and Aripiprazole in a Naturalistic Setting. Pharmacopsychiatry. 2020;53(1):30-5..
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Drug-Drug Interactions Between Lithium and Cardiovascular as Well as Anti-Inflammatory Drugs. Pharmacopsychiatry. 2020;53(5):229-34..
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Micronucleus frequency in buccal mucosa cells of patients with neurodegenerative diseases. Sci Rep. 2020;10(1):22196..
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The joint Nagasaki-Würzburg approach to challenges and perspectives in neuropsychiatric and regenerative research. J Neural Transm (Vienna). 2020;127(11):1447-8..
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ADORA2A variation and adenosine A(1) receptor availability in the human brain with a focus on anxiety-related brain regions: modulation by ADORA1 variation. Transl Psychiatry. 2020;10(1):406..
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Monoamine Oxidase A Hypomethylation in Obsessive-Compulsive Disorder: Reversibility By Successful Psychotherapy?. Int J Neuropsychopharmacol. 2020;23(5):319-23..
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Molecular genetic overlap between posttraumatic stress disorder and sleep phenotypes. Sleep. 2020;43(4)..
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Effect of CBT on Biased Semantic Network in Panic Disorder: A Multicenter fMRI Study Using Semantic Priming. Am J Psychiatry. 2020;177(3):254-6..
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Roadmap for Routine Pharmacogenetic Testing in a Psychiatric University Hospital. Pharmacopsychiatry. 2020;53(4):179-83..
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2019[ to top ]
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Predicting treatment outcome for anxiety disorders with or without comorbid depression using clinical, imaging and (epi)genetic data. Curr Opin Psychiatry. 2019;32(1):1-6..
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Human BDNF rs6265 polymorphism as a mediator for the generalization of contextual anxiety. J Neurosci Res. 2019;97(3):300-12..
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Variations in cardiovascular risk factors in people with and without migration background in Germany – Results from the STAAB cohort study. International Journal of Cardiology [Internet]. 2019;286:186-9. Available from: https://www.sciencedirect.com/science/article/pii/S0167527318341305.
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The South East European (SEE) - PTSD Study. Psychiatr Danub. 2019;31(2):210..
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The Combination of Lithium and ACE Inhibitors: Hazardous, Critical, Possible?. Clin Drug Investig. 2019;39(5):485-9..
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Association of NPSR1 gene variation and neural activity in patients with panic disorder and agoraphobia and healthy controls. Neuroimage Clin. 2019;24:102029..
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Role of the Allelic Variation in the 5-Hydroxytryptamine Receptor 1A (HTR1A) and the Tryptophan Hydroxylase 2 (TPH2) Genes in the Development of PTSD. Psychiatr Danub. 2019;31(2):256-62..
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[Therapeutic drug monitoring in neuropsychopharmacology : Summary of the consensus guidelines 2017 of the TDM task force of the AGNP]. Nervenarzt. 2019;90(5):463-71..
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Individual differences in human fear generalization-pattern identification and implications for anxiety disorders. Transl Psychiatry. 2019;9(1):307..
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Smoking Is Associated With Lower Dose-Corrected Serum Concentrations of Escitalopram. J Clin Psychopharmacol. 2019;39(5):485-8..
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Influence of two functional polymorphisms in NOS1 on baseline cortisol and working memory in healthy subjects. Nitric Oxide. 2019;88:45-9..
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A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders. Transl Psychiatry. 2019;9(1):150..
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Reduced spontaneous low frequency oscillations as measured with functional near-infrared spectroscopy in mild cognitive impairment. Brain Imaging Behav. 2019;13(1):283-92..
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Association Analysis of Maoa and Slc6a4 Gene Variation in South East European War Related Posttraumatic Stress Disorder. Psychiatr Danub. 2019;31(2):211-8..
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The Association of Catechol-O-Methyl-Transferase and Interleukin 6 Gene Polymorphisms with Posttraumatic Stress Disorder. Psychiatr Danub. 2019;31(2):241-8..
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Genetics of Anxiety Disorders. Curr Psychiatry Rep. 2019;21(3):16..
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Analysis of smoking behavior on the pharmacokinetics of antidepressants and antipsychotics: evidence for the role of alternative pathways apart from CYP1A2. Int Clin Psychopharmacol. 2019;34(2):93-100..
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A Candidate Gene Association Study of FKBP5 and CRHR1 Polymorphisms in Relation to War-Related Posttraumatic Stress Disorder. Psychiatr Danub. 2019;31(2):269-75..
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The DNA methylome in panic disorder: a case-control and longitudinal psychotherapy-epigenetic study. Transl Psychiatry. 2019;9(1):314..
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Hypermethylation of the serotonin transporter gene promoter in panic disorder-Epigenetic imprint of comorbid depression?. Eur Neuropsychopharmacol. 2019;29(10):1161-7..
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International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci. Nat Commun. 2019;10(1):4558..
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The Role of TaqI DRD2 (rs1800497) and DRD4 VNTR Polymorphisms in Posttraumatic Stress Disorder (PTSD). Psychiatr Danub. 2019;31(2):263-8..
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Associations of Gene Variations in Neuropeptide Y and Brain Derived Neurotrophic Factor Genes with Posttraumatic Stress Disorder. Psychiatr Danub. 2019;31(2):227-34..
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Associations between Polymorphisms in the Solute Carrier Family 6 Member 3 and the Myelin Basic Protein Gene and Posttraumatic Stress Disorder. Psychiatr Danub. 2019;31(2):235-40..
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Genetic Susceptibility to Posttraumatic Stress Disorder: Analyses of the Oxytocin Receptor, Retinoic Acid Receptor-Related Orphan Receptor A and Cannabinoid Receptor 1 Genes. Psychiatr Danub. 2019;31(2):219-26..
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Orexin in the anxiety spectrum: association of a HCRTR1 polymorphism with panic disorder/agoraphobia, CBT treatment response and fear-related intermediate phenotypes. Transl Psychiatry. 2019;9(1):75..
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Association of Neuropeptide S Receptor 1 and Glutamate Decarboxylase 1 Gene Polymorphisms with Posttraumatic Stress Disorder. Psychiatr Danub. 2019;31(2):249-55..
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